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Please note: Supplements are generally not FDA tested or approved. Some supplements can interfere with medications including blood pressure meds and anticoagulants. Do not delay seeking medical attention for medical concerns by taking supplements without medical advice. Combining supplements can increase the risk of toxicity and side effects. Statements and product contents have not been independently confirmed by MedicalResearch.com or Eminent Domains Inc. Please discuss any and all supplements you take or are considering taking with your health care provider. Ratings in this post are the opinions of the contributing writer and not MedicalResearch.com or Eminent Domains Inc. Do not take supplements discussed below if pregnant, nursing or might become pregnant unless directed by your provider. Keep out of reach of children. If for any reason you experience any adverse effects or any other form of discomfort from this product, immediately discontinue use of the product and consult with your doctor or visit the hospital, emergency room, or clinic.

Do GLP-1 Drugs Cause Muscle Loss? What Patients Should Know Before Starting Ozempic, Wegovy, or Zepbound

In the STEP 1 trial of semaglutide, the drug that became Wegovy, patients lost an average of 15% of their body weight over 68 weeks. About 39% of that loss came from lean tissue rather than fat. That number has fueled a wave of concern about "muscle loss" on Ozempic, Wegovy, and Zepbound. But lean tissue is not the same as skeletal muscle. It also includes water, organs, bone, and connective tissue, and most of what's lost during weight reduction tracks proportionally with the body getting smaller. In the same trial, relative lean mass actually went up. Whether a patient holds onto skeletal muscle and strength depends less on the drug itself and more on protein intake, resistance training, and how fast the weight comes off. This article is for educational purposes only and does not replace medical advice. Do not start, stop, or change a prescription medication without speaking with a licensed clinician.