MedicalResearch.com Interview with: HUANYU “LARRY” CHENG Ph.D. Associate Professor and Dorothy Quiggle Career Development Professor in Engineering James L. Henderson, Jr. Memorial Associate Professor of Engineering Science and Mechanics Penn State University MedicalResearch.com: What is the background for this study? Response: Although increasing efforts have been devoted to the development of non-invasive wearable electrochemical sweat sensors for monitoring physiological and metabolic information, most of them still suffer from poor stability and specificity over time and fluctuating pH and temperatures. laser-induced graphene is the low-cost platform for the early identification and continuous monitoring of different biomarkers for non-invasive disease diagnosis and treatment evaluation However, low sensitivity and limited surface area can limit the detection of ultra-low biomarker concentration in sweat or other fluids. As a result, a wide range of conductive nanomaterials has been incorporated into the porous structure of LIG to increase the available surface area, facilitate electron transfer, and enhance the electrocatalytic activity of the electrode but those nanomaterial modifications are hard to manufacture reproducibly, and they are not long-term stable. Therefore, it is highly desirable to develop a highly sensitive, selective, low-cost, and long-term stable flexible sensing platform for continuous and accurate healthcare monitoring.
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