Author Interviews, Environmental Risks, Infections, PNAS / 14.03.2024

MedicalResearch.com Interview with: Dr. Fangqun Yu PhD Senior Research Faculty Atmospheric Sciences Research Center University Albany, State University of New York https://www.albany.edu/~yfq   Dr. Arshad Arjunan Nair PhD Postdoctoral Associate Atmospheric Sciences Research Center University at Albany, State University of New York https://www.albany.edu/~an688965   MedicalResearch.com: What is the background for this study? What are the main findings? Dr. Fangqun Yu: Legionnaires’ disease is a severe form of pneumonia with a fatality rate of 10-25% caused by inhaling or aspirating Legionella, bacteria that thrive in built environment water systems. Those most vulnerable to this disease are male, over 50 years of age, have a history of smoking, have chronic respiratory diseases, diabetes, are immunocompromised, and/or minorities. The US observed a nearly nine-fold increase in Legionnaires’ disease between 2000 and 2018, with New York State having one of the highest increases in disease rates. The reasons for the increase in incidence were unclear prior to this study. In our study, we found: (1) Declining sulfur dioxide concentrations (SO2) are strongly correlated with the increase in legionellosis cases and a physical mechanism explaining this link is proposed, (2) A geostatistical epidemiological analysis links the disease with exposure to cooling towers, and (3) Climate and weather are ruled out as factors responsible for the long-term increase in case numbers (outside of seasonal trends). (more…)