19 Feb Pulmonary Fibrosis: High Resolution CT Diagnosis
MedicalResearch.com Interview with:
Ganesh Raghu, M.D.,FCCP, FACP
Professor of Medicine & Lab Medicine (Adjunct)
Division of Pulmonary & Critical Care Medicine
University of Washington(UW)
Director,CENTER for Interstitial Lung Disease (ILD),UW Medicine,
ILD, Sarcoid and Pulmonary Fibrosis Program
Co-Director, Scleroderma Clinic, UW Medical center(UWMC)
Seattle, WA 98195
MedicalResearch.com: What are the main findings of the study?
Dr. Raghu: In a subgroup of patients with typical clinical features of Idiopathic pulmonary fibrosis ( IPF) , further evaluation by a thorough evlauation by regional experts experienced in management of idiopathic pulmonary fibrosis and related diseases may lead to a diagnosis of idiopathic pulmonary fibrosis without the need for surgical lung biopsy if the HRCT features have a Possible-UIP pattern AND if there are no suspicion for environmental factors or collagen vascular diseases to explain the pulmonary fibrosis .
MedicalResearch.com: Were any of the findings unexpected?
- The HRCT pattern of Inconsistent- UIP does not exclude UIP in surgical lung biopsy
MedicalResearch.com: What should clinicians and patients take away from your report?
- General clinicians and confronted patients must familiarise themselves with clinical manifestations of Interstitial lung diseases , Idiopathic interstitial pneumonias and Idiopathic pulmonary fibrosis( IPF )
- These findings MUST not be extrapolated to the interpretation of HRCT pattern of possible UIP by general /community physicians and general radiologists
- Prompt referral to regional experts, experienced with management of ILD for an accurate diagnosis.
MedicalResearch.com: What recommendations do you have for future research as a result of this study?
Dr. Raghu: Ascertain sensitivity and specificity of the possible-UIP pattern in consecutive patients evalutated for ILD / idiopathic interstitial pneumonia
Published online February 18, 2014 http://dx.doi.org/10.1016/S2213-2600(14)70011-61