Alzheimer's - Dementia, Author Interviews, Biomarkers / 11.12.2024

MedicalResearch.com Interview with: Alberto J. Espay, MD, MSc, FAAN Professor of Neurology Director and Endowed Chair Gardner Family Center for Parkinson's disease and Movement Disorders University of Cincinnati Academic Health Center MedicalResearch.com: What is the background for this study? What are the main findings Response:  Because aducanumab, lecanemab, and donanemab were only in a minority of anti-amyloid treatments showing a benefit, I was interested in finding out what makes them special. It turns out that they not only clean the brain from amyloid, like other monoclonal anti-Aβ antibodies, but they also increase Aβ42 in the spinal fluid, which is a measure of the normal protein in the brain. Everyone with Alzheimer’s has low Aβ42 levels because this protein clumps into amyloid plaques. I tested the hypothesis that increasing Aβ42 could explain the cognitive outcomes at least as well as decreasing amyloid, and that’s exactly what we found. This suggests that restoring the normal protein levels, Aβ42, may explain why some anti-amyloid treatments (presumably those that increased those levels the most) come with benefits. (more…)
Electronic Records / 11.12.2024

MedicalResearch.com Interview with: Prof. Adam J. Rose Shuli Brammli-Greenberg and Adam J. Rose share senior authorship. Faculty of Medicine, Hebrew University of Jerusalem Beit-Horon, Jerusalem, 9093500, Israel MedicalResearch.com: What is the background for this study? Would you briefly explain what is meant by the Elixhauser Comorbidity Model? Response: Patients admitted to the hospital can have very different levels of illness severity. In addition, different hospitals may admit different numbers of very sick patients. Therefore, comparing two hospitals regarding something like length of stay or in-hospital mortality is not valid unless one adjusts for the illness burden of the population of patients at each hospital. Risk adjustment is the name for the process of building a model to predict the risk of each patient for a particular outcome, such as mortality or readmission, based on what is known about them and their illness burden. By summing all the risks of patients at a hospital, one gets an aggregate sense of the illness burden at the hospital, and different hospitals can be compared. The Elixhauser Comorbidity Model is a widely-used risk adjustment model which performs well in the sense that it is very predictive of outcomes like mortality. It also has the advantage of being calculated from diagnosis codes, which are widely available data for hospitalized patients. (more…)
Exercise - Fitness, Rheumatology / 10.12.2024

  Arthritis is a common condition that can cause pain, stiffness, and swelling in the joints, affecting mobility and quality of life. Engaging in regular physical activity is one of the effective ways to manage and potentially prevent the onset of arthritis. Including specific activities in your routine can improve joint health and reduce the risk of developing arthritis. Exercise not only strengthens the muscles around the joints but also promotes flexibility and balance, which are critical factors in minimizing arthritis symptoms. This article explores a variety of physical activities that can be beneficial for joint health, offering an accessible approach to arthritis prevention for individuals of all fitness levels. (more…)
Author Interviews, Medical Imaging / 05.12.2024

MedicalResearch.com Interview with: Miriam A. Bredella, MD, MBA Bernard and Irene Schwartz Professor of Radiology & Vice Chair for Strategy Associate Dean for Translational Science Director, Clinical and Translational Science Institute NYU Grossman School of Medicine NYU Langone Health Translational Research Building 743 New York, NY 10016   MedicalResearch.com: What is the background for this study? Response: We perform >80 million CTs every year in the US, and there is a lot of information on these CTs that is not used and “thrown away.” Opportunistic imaging or opportunistic screening with the help of AI takes advantage of this information and automatically detects and quantifies vascular calcification, bone mineral density, abdominal fat or muscle mass. In our study, we wanted to detect whether calcification of the abdominal aorta, quantified using AI, could predict coronary artery calcification and major cardiovascular events (e.g. myocardial infarction, cardiac revascularization, stroke, or death). (more…)
Author Interviews, Cancer Research, NEJM, NIH, OBGYNE / 05.12.2024

MedicalResearch.com Interview with: Diana W. Bianchi, M.D. Senior Investigator Center for Precision Health Research Director, Eunice Kennedy Shriver National Institute of Child Health and Human Development National Institutes of Health MedicalResearch.com: What is the background for this study? Response: The ability of prenatal cell-free DNA (cfDNA) sequencing to incidentally detect maternal cancers has been demonstrated by several retrospective studies from commercial or national laboratories. However, there are no standardized approaches to the identification and medical management of prenatal screening results that might indicate a maternal cancer. We sought to prospectively identify DNA sequencing patterns and other biomarkers that could distinguish which women with nonreportable or unusual cfDNA sequencing results had cancer and to determine the best approach for diagnostic work-up of pregnant people who receive these results. (more…)
Supplements, Vitamin C, Vitamin D, Vitamin E, Vitamin K / 04.12.2024

Be sure to discuss your specific use of vitamins and supplements with your health care provider.  Vitamins and supplements may have side effects and/or interfere with other medications. Vitamins and supplements may also be toxic in higher doses. Over-the-counter vitamins and supplements may not be FDA approved or contain inaccurate labeling information. Every cell, every organ and every function in our bodies depends on nutrients. From supporting the immune system to keeping bones strong, stabilising energy levels and even enhancing mental clarity, vitamins and minerals are essential for us to function properly. But even with a balanced diet, ensuring we get all the nutrients we need can be a challenge. The rise of processed foods, long storage times and agricultural practices, leave gaps in what we eat. The ideal multivitamin formula can vary significantly by gender and age, as different groups have unique nutritional needs. The best multivitamin for men will typically include ingredients that provide additional support for heart health and muscle function, such as supplements with higher levels of vitamin E and magnesium. Ingredients such as coenzyme Q10, which is known to support cardiovascular health, and lycopene, which benefits prostate health, are also found in some products. Particularly important for women are nutrients such as folate and biotin that are important for reproductive health and for hair, skin and nails. The best multivitamin for women may also include iron, especially for those who may have higher needs due to menstruation. For the elderly, the focus is on nutrients that compensate for the natural decline in absorption and physiological changes. For example, what is the best multivitamin for a 70-year-old woman? Probably one with higher levels of vitamin B12 and vitamin D. Formulas for older people are also often gentle on the stomach and designed for better absorption, making them suitable for sensitive digestive systems. (more…)
Author Interviews, OBGYNE / 04.12.2024

MedicalResearch.com Interview with: John W. AyersJohn W. Ayers, PhD, MA Altman Clinical Translational Research Institute University of California San Diego, La Jolla MedicalResearch.com: What is the background for this study? Response: Crisis pregnancy centers (CPCs) are frequently at the center of news and policy debates, yet little data exists about where they operate or what they actually do. To address this gap, we developed ChoiceWatch.org, a tool that systematically collected and analyzed over 470,000 webpages from CPC websites. In our study published in JAMA Internal Medicine, we used ChoiceWatch.org, to answer fundamental questions, such as how many crisis pregnancy centers operate in the U.S., where they are located, and what services they advertise. (more…)
Author Interviews, COVID -19 Coronavirus, Mental Health Research, Pulmonary Disease / 30.11.2024

MedicalResearch.com Interview with: Sean B. Fain, Ph.D. Professor and Vice Chair for Research Department of Radiology Affiliate Appointments BME and ECE University of Iowa Iowa City, IA MedicalResearch.com: What is the background for this study? Response: This study uses MRI to investigate connections between lung and brain function. We employ an advanced MRI technique that uses hyperpolarized xenon gas as a contrast agent. This approach allows us to image which parts of the lung are effectively inhaling xenon gas and which parts are not (i.e. ventilation). Additionally, xenon provides insights into lung gas exchange (i.e. oxygen transfer into and out of the blood), as it freely diffuses into alveolar tissue and binds to red blood cells. Using this technology, we hypothesized that the severity of lung injury in individuals with Long COVID would correlate with the degree of cognitive dysfunction and brain imaging. (more…)
Cognitive Issues, Supplements / 28.11.2024

Editor's note: Most Nootropics are not FDA tested or approved. Supplements, including those sold as cognitive enhancers, may have side effects. Please do not take nootropic medications or supplements without discussing with your health care provider first. Have you ever wished for a way to sharpen your focus, improve your memory, or simply stay mentally clear throughout the day? Nootropics, often referred to as "cognitive enhancers," might be the solution you've been curious about. These supplements are gaining popularity among students, professionals, and anyone looking for that extra edge in mental performance. But how exactly do they work, and are they right for you? What Are Nootropics? Nootropics are substances—either natural or synthetic—that are designed to enhance cognitive functions like memory, creativity, and focus. Some of these might be things you’re already familiar with, like caffeine, while others are lesser-known compounds or herbal extracts. A defining feature of nootropics from the likes of Simply Nootropics is that they are thought to support brain function without causing significant side effects. They’re not about forcing your brain into overdrive but rather optimising its natural processes. (more…)
Mental Health Research / 25.11.2024

 If you have experienced suicidal thoughts or have lost someone to suicide and want to seek help, you can contact the Crisis Text Line by texting "START" to 741-741 or call the Suicide Prevention Lifeline at 800-273-8255. Handling High Patient Demands   Mental health practices are seeing more new patients than ever before. Growing awareness of mental health issues has encouraged more people to seek help, but this increase has created challenges for providers. Many practices are now dealing with long waitlists and overworked staff, which can affect the quality of care and overall patient satisfaction.   To manage these issues, mental health professionals need clear strategies. These approaches must ensure that new patients get the help they need while practices run smoothly. Read on!

Why Patient Demand Is Rising

The demand for mental health services has grown for several reasons. More people now recognize the importance of mental health, and the stigma around seeking help has decreased. At the same time, global challenges and daily stress have caused more individuals to face anxiety and depression.   In smaller communities, a lack of an available health professional adds to the problem. For example, a single counselor in a town may receive far more appointment requests than they can handle. This creates delays for patients and stress for providers. Understanding the reasons behind this increased demand is key to finding solutions. (more…)
Author Interviews, Cannabis, JAMA, Mental Health Research / 22.11.2024

MedicalResearch.com Interview with: Belén Blasco PhD Student in Neuroscience - MD Psychiatry Clinical and Translational Sciences (CaTS) Lab Integrated Program in Neuroscience McGill University | Douglas Research Centre Montreal, Canada MedicalResearch.com: What is the background for this study? Response: Our research is centered on uncovering the early brain changes that might contribute to psychosis development. Using innovative brain imaging techniques, we aimed to measure synapsis in individuals with early psychotic symptoms or who are considered at high clinical risk. Synapses are the crucial points of connection between neurons, allowing communication across the brain. A key aspect of our study was to understand how lifestyle factors, like cannabis use, might impact these brain changes, particularly since cannabis consumption has been associated with an increased risk of developing psychosis in young people. (more…)
Author Interviews, Genetic Research, Leukemia, Personalized Medicine / 12.11.2024

MedicalResearch.com Interview with: Professor Ong Sin Tiong Cancer & Stem Cell Biology Signature Research Programme Duke-NUS Medical School, Singapore Dr Yu Mengge Research Fellow, Cancer & Stem Cell Biology Signature Research Programme Duke-NUS Medical School MedicalResearch.com: What is the background for this study? Response: The background of this study is rooted in the observation that certain genetic variations among East Asian populations, notably the BIM deletion polymorphism (BDP), impact treatment outcomes in chronic myeloid leukaemia (CML). Patients with the BDP show resistance to conventional treatments, specifically tyrosine kinase inhibitors like imatinib. This resistance stems from the variant's role in promoting cancer cell survival, which leads to more aggressive disease progression. (more…)
Author Interviews, Neurology, Sexual Health, STD / 06.11.2024

MedicalResearch.com Interview with: Sagar S. Patel, MBS Department of Medical Education Geisinger Commonwealth School of Medicine Scranton, PA 18509 MedicalResearch.com: What was the background for this research? Response: Syphilis is a sexually transmitted infection that is caused by a gram-negative bacterium called Treponema pallidum. This infection promotes the cell death of microglia and can cause a variety of symptoms. It is commonly observed in developing countries such as sub-Saharan Africa. Neurosyphilis is a complication of syphilis that affects the central nervous system (CNS). The CNS undergoes multiple stages of deterioration and can include personality changes and hearing abnormalities. Diagnosing neurosyphilis is challenging because its symptoms mimic other neurodegenerative diseases. Diagnosis relies on clinical studies, cerebrospinal fluid (CSF) analysis, and neuroimaging techniques. (more…)
AI and HealthCare, Author Interviews, Breast Cancer, Genetic Research / 06.11.2024

MedicalResearch.com Interview with: Prof. Dina Schneidman-Duhovny PhD Academic researcher Hebrew University of Jerusalem MedicalResearch.com: What is the background for this study? What are the main findings? Response: The study analyzed genetic data of 12 families (~ 40 patients) with high incidence of breast cancer cases. Most families originate from ethnic groups that are poorly represented in public resources. All participants were tested negative to all known breast cancer predisposing genes. We developed a novel approach to study genetic variants utilizing state-of-the-art deep learning models tailored for analysis of familial data. The study highlighted 80 high-risk genes (out of > 1200 genes) and narrowed down on a group of 8 genes circulating in 7 out of 12 families in the study. These genes are involved in a cellular organelle called the peroxisome and play a role in fatty acids metabolism. We show that  these genes significantly affect breast cancer survival and use 3-dimensional protein structural analysis to illustrate the effect of some of the variants on protein structure. These provide strong evidence of the peroxisome involvement in breast cancer predisposition and pathogenicity, and provide potential targets for patient screening and targeted therapies. (more…)
Author Interviews, Ovarian Cancer / 04.11.2024

MedicalResearch.com Interview with: Alessia Baccarini, PhD Assistant Professor Dept. of Immunology and Immunotherapy (DII) Icahn School of Medicine at Mount Sinai New York, New York 10029 MedicalResearch.com: What is the background for this study? Response: Ovarian cancer is characterized by a complex tumor microenvironment (TME) that significantly contributes to resistance against immunotherapy, particularly immune checkpoint blockade (ICB) therapies like anti-PD-1. Understanding the extracellular signals—such as cytokines and chemokines—that ovarian cancer cells utilize to create an immunosuppressive TME is critical for improving treatment outcomes. Our research focuses on elucidating how these signaling factors contribute to tumor growth and immune evasion. We utilized a novel genomic functional approach called Perturb-map to study intratumoral heterogeneity (ITH) in ovarian cancer within a mouse model, allowing us to investigate the communication between ovarian cancer cells and immune cells.  (more…)
Dermatology, Plastic Surgery / 04.11.2024

laser-hair-removal.jpg   Imagine stepping out of the shower and instantly feeling like your skin is made of pure silk—never having to shave or wax again.  That’s what laser hair removal may do for you. It’s the perfect choice for modern women with packed schedules. And on top of hair-free and smooth skin, it also boosts your confidence and saves you money and time. It’s time to ditch those painful wax strips. Keep reading to find out why laser hair removal is the lifestyle upgrade you need.
  1. Live Hair-Free Without Constant Upkeep
This is probably the best benefit you’ll enjoy from laser hair removal. Imagine living hair-free without endless hair removal routines. With traditional methods like waxing, sugaring, or shaving, hair may grow back in just a few days. With laser treatment, however, regrowth cycles vary but are significantly longer. Some of our patients go for maintenance sessions every several months, while others, annually. If hair does resurface, it will be thinner and lighter in color—hence a lot less noticeable. (more…)
Brain Cancer - Brain Tumors, Immunotherapy, Vaccine Studies / 04.11.2024

brain-cancer-glioblastoma Glioblastoma is one of the most challenging cancers to treat due to its aggressive nature and resistance to standard therapies. In recent years, however, the field of glioblastoma immunotherapy has made significant strides, introducing innovative approaches like oncolytic viruses and brain cancer vaccines. These emerging treatments aim to engage the immune system in the fight against glioblastoma, offering new avenues for improving patient outcomes and extending survival rates.

The Current State of Glioblastoma Treatment

  With a median survival rate of only 12-15 months, glioblastoma patients face difficult odds. Traditional treatments often manage to slow tumor growth temporarily, but recurrence is common. This grim reality has motivated researchers to explore innovative therapies that leverage the body’s immune system, including oncolytic viruses and personalized vaccines.

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Author Interviews, Cancer Research, Leukemia, Stem Cells / 01.11.2024

MedicalResearch.com Interview with: Eirini Papapetrou, MD, PhD Professor of Oncological Sciences Professor of Medicine, Hematology and Medical Oncology Director, Center for Advancement of Blood Cancer Therapies Co-Director, Stem Cell Engineering Core Icahn School of Medicine at Mount Sinai New York, NY 10029   MedicalResearch.com: What is the background for this study? What are the main findings? Response: RAS in the most commonly mutated oncogene in human cancers. Particularly in acute myeloid leukemia, about one third of cases have RAS mutations. We set out to understand the role of these mutations in the development of leukemia and in response to treatment. We found that RAS mutations happen late in the course of the disease as progression mutations because they are acquired by more mature leukemic cells coming from preexisting leukemia stem cells (LSCs). Importantly, these more mature cells, upon acquisition of RAS mutations, become leukemia stem cells (LSCs) with different properties than the previous LSCs. Most critically, they develop resistance to a recently FDA-approved drug for the treatment of leukemia, venetoclax (VEN). In addition, these RAS-mutated LSCs give rise to leukemia cells with monocytic differentiation. Both RAS mutations and monocytic differentiation of AML have previously been associated with VEN resistance in clinical studies. We show that it is the RAS mutations that cause both the monocytic differentiation and the VEN resistance. Thus, poor patient outcomes after VEN therapy are driven by RAS mutations and not by monocytic disease.  (more…)
Author Interviews, Health Care Systems, JAMA, Pharmacology, University of Pittsburgh / 31.10.2024

MedicalResearch.com Interview with: Katie J. Suda, PharmD, M.S., FCCP Professor of medicine with tenure Associate Director, Center for Pharmaceutical Policy and Prescribing University of Pittsburgh School of Medicine MedicalResearch.com: What is the background for this study? Response: Our pharmaceutical supply chain is global where the manufacturing process for one drug may occur in multiple countries. Sometimes there are breakdowns in the pharmaceutical supply chain which may threaten access to medicines. Breakdowns in the supply chain occur for medicines manufactured in the U.S. and by international partners. While breakdowns in the supply chain occur for hundreds of drugs each year, not all result in a decrease in available supply (a “drug shortage”) because of action taken by manufacturers, pharmacies and drug regulators (e.g., the U.S. Food and Drug Administration [FDA]). Drug shortages are a critical concern to public health as pharmacies, clinicians, and patients struggle to identify safe and effective alternatives. In addition, drug shortages have been associated with adverse patient outcomes and medication safety events. Recently, drug shortages have gotten worse with shortages occurring with increasing frequency and lasting longer. There has also been a shift in the types of medicines in shortage from drugs primarily used in hospitals, such as injectables, to oral medicines frequently used to manage outpatient conditions. Countries have different regulatory authority and policy which may impact how drug supply chain breakdowns result in drug shortages. We wanted to know if there are differences between the U.S. and Canada in the frequency that national drug shortages occur after supply chain breakdowns are reported in both countries. Canada is a good comparator to the U.S. because Canada has similar drug regulatory standards and manufacturing inspections. Prescription drug coverage is also similar for the two countries where half of prescriptions are reimbursed through public insurance and half through private insurance and out-of-pocket. (more…)
Author Interviews, Diabetes, Kidney Disease, Nature, Semaglutide / 31.10.2024

MedicalResearch.com Interview on publication of: Prof. dr. H.J. (Hiddo) Lambers Heerspink Clinical Pharmacologist Faculty of Medical Sciences University of Groningen MedicalResearch.com: What is the background for this study? What are the main findings? Response: The diabetes drug semaglutide, also known as Ozempic, has a positive effect for patients with chronic kidney damage and obesity. The amount of protein in their urine decreased, as did the degree of inflammation of their kidneys and their blood pressure. Hiddo L. Heerspink got the idea for this study at the beginning of the corona pandemic. Earlier, he had discovered that another class of drugs against diabetes-2, the so-called SGLT2 inhibitors also appeared to work well for patients with chronic kidney damage without diabetes. He therefore wanted to investigate whether semaglutide would also work positively for patients with chronic kidney disease and obesity. (more…)
Cannabis, OBGYNE, Pediatrics / 30.10.2024

MedicalResearch.com Interview with: Sarah Keim, PhD Associate Professor, Epidemiology College of Public Health The Ohio State University MedicalResearch.com: What is the background for this study? Response: Marijuana is the illicit substance most commonly used during pregnancy, and use is increasing. Some evidence suggests that marijuana is associated with deficits in executive function and increased delinquent behavior in school-age children and adolescents, with potential downstream impacts on achievement and social functioning. However, this evidence comes largely from only 2 studies several decades old. Today cannabis is more than 10 times more potent than it was several decades ago. (more…)
Anesthesiology, Pain Research / 29.10.2024

MedicalResearch.com Interview with a Vertex spokesperson.   MedicalResearch.com: What is the background for this study? What are the main findings?
  • We presented Phase 3 data for our investigational, oral pain signal inhibitor, suzetrigine, at ANESTHESIOLOGY 2024, the American Society of Anesthesiologists’ annual meeting. The Phase 3 data were previously announced in January 2024, and this is the first time the findings were presented to the medical community. The data were featured in the “Best Abstracts” session at the meeting.
  • Our Phase 3 acute pivotal program for suzetrigine included two randomized, double-blind, placebo-controlled, pivotal trials, one following abdominoplasty surgery and one following bunionectomy surgery, as well as a single arm safety and effectiveness study which enrolled patients with a broad range of surgical and non-surgical pain conditions. All three studies demonstrated compelling and consistent efficacy and safety across multiple acute pain conditions and settings.
  • Together, the data demonstrate suzetrigine’s potential to offer a safe, well tolerated and effective alternative to the current acute pain treatment paradigm, without addictive potential.
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Aging, Nursing Homes / 28.10.2024

Nursing homes of a high standard can have great benefits for residents. When selecting a nursing home or rehabilitation center, families often rely on facility ratings to evaluate the quality of care provided. Understanding the ratings associated with nursing homes can offer insights into the quality of care residents receive, helping families make well-informed decisions.

Key Aspects of Ratings for Nursing Homes

Nursing home ratings typically cover several essential areas of care, including staffing, safety, and resident satisfaction. The high Casa de Oro Center ratings reflect its commitment to providing a safe, supportive, and nurturing environment for residents. Families evaluating this facility should consider the following aspects:
  • Staffing and Responsiveness: Adequate staffing is crucial for delivering timely and effective care. High ratings in this area indicate that the nursing home maintains sufficient staff-to-resident ratios, ensuring residents receive the attention and assistance they need promptly.
  • Safety and Hygiene Protocols:  High safety ratings signify the facility’s adherence to strict hygiene protocols, which are essential in preventing the spread of infections and protecting residents’ health.
  • Resident Satisfaction: Feedback from residents and their families plays a significant role in overall ratings. High satisfaction scores suggest that residents feel comfortable, valued, and well-supported, contributing to their emotional well-being and overall quality of life.
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Infections / 28.10.2024

MedicalResearch.com Interview with: Dr. Asaf Levy Senior Lecturer, Assistant Professor Plant Pathology and Microbiology The Robert H Smith Faculty of Agriculture, Food and Environment Hebrew University of Jerusalem MedicalResearch.com: What is the background for this study? Response: Bacteria encode many compounds used to target neighboring microbes or cause disease in hosts, including humans. Classic antibiotics (small molecules) are one well-studied group of antimicrobials encoded by bacteria. A less-studied group consists of short protein toxins. These proteins are produced by bacteria and injected into target cells to kill them. In this study, we focused on a group of protein toxins called polymorphic toxins, which carry a short toxin domain at their end, which we termed “PTs” (an acronym for polymorphic toxins) and are roughly 100 amino acid long. We developed a new algorithm to scan 107,000 bacterial genomes and discover novel PTs encoded by these bacteria. We then experimentally confirmed 9 new PT families that can kill bacteria and pathogenic fungi, including human pathogens, such as Candida auris and Aspergillus fumigatus. We saw that two of the toxins kill cells by degrading their DNA. (more…)
Author Interviews, Mental Health Research, University of Michigan / 27.10.2024

MedicalResearch.com Interview with: Daniel J. Kruger, PhD University of Michigan MedicalResearch.com: What is the background for this study? Response: A team of researchers from the University of Michigan and University at Buffalo teamed up with psychedelic advocates and therapists to document some of the challenges with psychedelics. They surveyed over a thousand psychedelic users about their adverse experiences and the experiences they have heard from others. Most reported being frightened, sadness, loneliness, and feeling their body tremble or shake at times. Some people experienced panic, paranoia, felt that they are dead, or that the state they were in would last forever. One in ten participants had adverse physical reactions.  For most people having these experiences, they are rare or happen sometimes, but they are still significant. Most of the people that experienced a severe adverse event did not have guidance from someone who was knowledgeable about psychedelics. A small portion of participants knew about an incident of inappropriate sexual contact by a psychedelic sitter, guide, or practitioner, the perpetrators were mostly underground guides and friends or acquaintances. (more…)
Author Interviews, COVID -19 Coronavirus, JAMA, OBGYNE, Pediatrics / 16.10.2024

MedicalResearch.com Interview with: Eleni G. Jaswa, MD, MSc Assistant Professor, Ob/Gyn, Reproductive Science UCSF MedicalResearch.com: What is the background for this study? Response: Some infections during pregnancy have been associated with abnormal neurodevelopment in children. This is likely due to the infection itself, or the maternal immune system response to infection. We sought to determine whether maternal COVID-19 infection during pregnancy, a now common occurrence, was associated with changes in children's neurodevelopment out to 24-months-old, compared to control children not exposed to maternal COVID-19 in utero. (more…)