For Low Risk Patients, USPSTF Does Not Recommend Adding ECG Screening to Standard Risk Management Assessment

MedicalResearch.com Interview with:

Dr. Michael Barry MD Director of the Informed Medical Decisions Program Health Decision Sciences Center at Massachusetts General Hospital Physician at Massachusetts General Hospit Professor of Medicine,Harvard Medical School

Dr. Barry

Dr. Michael Barry MD
Director of the Informed Medical Decisions Program
Health Decision Sciences Center at Massachusetts General Hospital
Physician at Massachusetts General Hospit
Professor of Medicine,Harvard Medical School

MedicalResearch.com: What is the background for this study? What are the main findings?

Response: Cardiovascular disease (CVD), which can lead to heart attack and stroke, causes 1 in 3 deaths among adults in the United States. The Task Force reviewed the latest research on whether adding an electrocardiogram—or ECG, which is a test that records a person’s heart activity—to the standard ways we measure CVD risk can help prevent heart attack and stroke in people who do not have symptoms and are generally healthy, as well as people who are already at risk for these conditions.

The evidence shows that adding screening with ECG to the ways we already measure CVD risk is unlikely to help prevent heart attack or stroke in people at low risk. It can also cause harms—such as those from follow-on procedures like angiography and angioplasty, which can lead to heart attack, kidney failure, and even death. As a result, the Task Force recommends against screening with ECG for this group.

For those who might benefit the most—people who are already at medium or high risk of CVD—there is not enough evidence to say whether or not adding screening with an ECG to standard care helps prevent heart attack and stroke. This is an area where we need more research.  Continue reading

Obese Women Remain at Risk For Heart Disease, Even When Metabolically Healthy

MedicalResearch.com Interview with:
Nathalie Eckel, MSc

German Diabetes Center
Düsseldorf, Germany 

MedicalResearch.com: What is the background for this study?

 Response: Obesity is associated with metabolic disorders such as diabetes, high blood pressure and hypercholesterolemia, and with a higher risk of cardiovacular disease compared to normal weight. However, there is also the phenomenon of the so-called “metabolically healthy obesity” and “metabolically unhealthy normal-weight”. So far it has been unclear how metabolic risk factors change over time in metabolically healthy people depending on body weight and what cardiovascular disease risk results from this.

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Think Vitamin Supplements Improve Your Heart Health? Think Again!

MedicalResearch.com Interview with:
“Pills Vitamins Macro April 22, 2012 4” by Steven Depolo is licensed under CC BY 2.0David J.A. Jenkins, MD, PhD, DSc
Professor and Canada Research Chair in Nutrition and Metabolism
Department of Nutritional Sciences
University of Toronto 

MedicalResearch.com: What is the background for this study?

Response: The study was requested by the editor of JACC (Dr. Valentin Fuster) due to the widespread use of vitamin and mineral supplementation by the public and the requirement to know if there were any benefits or harms for cardiovascular disease.

Our study was a follow-up to the US Preventive Services Task Force 2013 recommendations.

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Study Finds Plant-Based Diet Can Reduce Cardiovascular Death by 40%

MedicalResearch.com Interview with:
“Vegetarian Skewers” by Geoff Peters is licensed under CC BY 2.0Hana Kahleova, M.D., Ph.D.
Director of clinical research
Physicians Committee for Responsible Medicine
Washington, DC 20016 

MedicalResearch.com: What is the background for this study? What are the main findings? 

Response: In this study, my research team and I reviewed multiple clinical trials and observational studies to determine the links between diet and cardiovascular disease (CVD) risk. We found that a healthy diet can reduce the risk of heart attack by more than 80 percent—something no drug has ever accomplished.

We also found strong and consistent evidence that plant-based dietary patterns (with few or no animal products and rich in fruits, vegetables, grains, and legumes) can prevent and even reverse atherosclerosis and decrease other markers of CVD risk, including blood pressure, cholesterol, and weight. We found that a plant-based diet can reduce the risk of death from cardiovascular disease by about 40 percent overall.  Continue reading

CVD Risk: Metabolic Health, not BMI, determined risk in young women

MedicalResearch.com Interview with:
Dr Søren Skøtt Andersen and Dr Michelle Schmiegelow
Study done in collaboration between Roskilde University Hospital
and Gentofte University Hospital in Denmark.

MedicalResearch.com: What are the main findings of the study?

Answer: The main finding of this study of young women was that a body mass index above or equal to 25 kg/m2 in metabolically healthy women was not associated with an increased risk of cardiovascular events (myocardial infarction or ischemic stroke) within 5 years of follow-up. A BMI >= 25 kg/m2 in women with any metabolic disorder was associated with a 4-fold significant increased risk of the end-point. As increasing BMI is strongly associated with risk of developing metabolic disorders, the key message of this study is to stress the importance of preventing the development of metabolic disorders in overweight/obese women during this possible “window of opportunity”.
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