Author Interviews, COVID -19 Coronavirus / 29.09.2020 Interview with: Gizem Kilic MSc, PhD Candidate} Radboud University Medical Center Department of Internal Medicine Laboratory of Experimental Internal Medicine Nijmegen What is the background for this study? Response: Having emerged in Wuhan, China in December 2019, novel coronavirus infection 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) has become a major health crisis affecting worldwide. Although the disease symptoms are mild in most of the cases, it is known that advanced age and co-morbidities such as diabetes and cardiovascular diseases increase the risk of disease severity. Moreover, epidemiological data from different countries indicated that the mortality rate is higher in males compared to females. There are reports suggesting that some viral and bacterial infection are sex-biased; however, why males are more susceptible to develop severe COVID-19 infection has not been fully understood yet.  (more…)
AHA Journals, Author Interviews, Blood Pressure - Hypertension, Exercise - Fitness / 22.02.2019 Interview with: Michael J. Wheeler Baker Heart and Diabetes Institute Melbourne, Victoria, Australia What is the background for this study? What are the main findings? Response: We conducted this study because separate lines of inquiry have determined that a bout of exercise can acutely lower blood pressure, and more recently that prolonged sitting can increase blood pressure over the space of a day. We wanted to know whether the blood pressure lowering effects of an exercise bout would be diminished by a subsequent period of prolonged sitting or enhanced by a subsequent period of sitting that is regularly interrupted with short walking breaks. We found an additive blood pressure lowering effect when exercise was combined with breaks in sitting as opposed to exercise plus prolonged sitting. However, this was only true for women. Men had equal blood pressure lowering effects following exercise regardless of whether-or-not subsequent sitting was interrupted (more…)