Author Interviews, Dermatology, Technology / 19.09.2018

MedicalResearch.com Interview with: photostimulation of hair growthHan Eol Lee Ph.D. Flexible and Nanobio Device Lab. Department of Materials Science and Engineering KAIST MedicalResearch.com: What is the background for this study? Response: Numerous people around the world have suffered from alopecia, which leads to aesthetic issues, low self-esteem, and social anxiety. With the population expansion alopecia patients from middle-age down even to the twenties, a depilation treatment is expected to have social and medical impacts on billions of patients. The causes of alopecia are generally known to be heredity, mental stress, aging, and elevated male hormone. Therapeutic techniques such as thermal, electrical, pharmacological, and optical stimulation have been proposed to treat hair problems. Among them, laser stimulation to hair-lost regions is a promising technique, activating the anagen phase and the proliferation of hair follicles without side effects. However, this laser stimulation technique has drawbacks, such as high power consumption, large size, and restrictive use in daily life (e.g., the difficulty of microscale spatial control and the long time exposure of high-energy laser). 
Dermatology, PNAS, Weight Research / 02.04.2014

Professor Rodney Sinclair University of Melbourne and Epworth Hospital Melbourne, VIC, AustraliaMedicalResearch.com Interview with: Professor Rodney Sinclair University of Melbourne and Epworth Hospital Melbourne, VIC, Australia   MedicalResearch.com: What are the main findings of the study? Answer: Activation of Wnt signalling promoted hair growth and fat growth.  Inhibition of Wnt signalling reduces fat growth and hair growth.  We looked at the fat layer on the scalp.  It was reduced by 50% over the bald areas of alopecia areata.  The patch of alopecia areata we looked at was new- only appeared a few days earlier and so the changes in fat thickness are rapid. What is interesting is that the fat layer is dynamic, and significant fluctuations can occur in a rapid period of time in sync with the hair cycle.  It is also interesting that ligands for BMP6 and IGF2 are pro-adipogenic. There are a couple of bigger questions that earlier media reports did not focus on- namely upstream factors regulating the hair cycle clock and the beauty of synchronization of fat and hair growth for seasonal thermal insulation.