MedicalResearch.com Interview with:
Imperial College Healthcare NHS Trust
London, United Kingdon
MedicalResearch.com: What is the background for this study? What are the main findings?
Response: Iron status has previously been associated with risk of various types of cardiovascular disease, including stroke. However, the observational research methodologies that identified these associations can be affected by confounding from environmental factors and reverse causation.
We used randomly allocated genetic variants that affect iron status to investigate its effect on risk of different types of ischemic stroke, and found evidence to support that higher iron status increases risk of cardioembolic stroke.