Dermatology / 02.08.2024

Editor's note:  Not all dark or discolored areas on the skin are benign.  Some may be cancerous or precancerous.  Please consult your dermatologist or  health care provider before beginning any depigmenting treatment and  follow up as the provider directs. Depigmenting treatments are not FDA approved and may have side effects, including allergic reactions and hyperpigmentation. They should not be used if pregnant, nursing or planning to become pregnant.  Please consult your provider for specific medical advice. What Are Dark Spots and Why Do They Appear? Hyperpigmentation, or "dark spots," are patches of skin that seem darker than the surrounding tissue. Although it can affect any region of the body, the face, arms, and hands are the most frequently affected areas. These spots form when cells known as melanocytes, which produce melanin, are overactive. The overproduction of melanin, the pigment responsible for skin color, leads to patches or spots that appear darker. Several factors contribute to the development of dark spots. One of the main causes is sun exposure since UV rays hasten the formation of melanin. Hyperpigmentation can also be brought on by hormonal changes, such as those brought on by birth control drugs or pregnancy. Additionally, skin injuries, acne, and other forms of inflammation can result in post-inflammatory hyperpigmentation. Using a dark spot remover can help mitigate these spots, but understanding their root causes is crucial for effective prevention and treatment. (more…)
Author Interviews, Genetic Research, Ophthalmology, Science / 12.03.2021

MedicalResearch.com Interview with: eye-eyecolor-geneticsDr Pirro Hysi Senior Lecturer in Ophthalmology Kings College London MedicalResearch.com: What is the background for this study? Response: - Iris (eye) color is an important human trait. It is one of the main features that makes our faces unique and recognizable. Iris color is similar to other pigmentatio traits, like hair and skin color, in that it is determined by the concentration and relative ratios of the melanin pigment. Pigmentation traits are roughly determined by several of the same genes regulating pigmentation, but many other genes seem to selectively determine pigmentation in any of these tissues. (more…)