Author Interviews, JAMA / 26.04.2014
Suicide and Self-Harm: Genetic and Environmental Influences Overlap
MedicalResearch.com Interview Invitation
Karin J. H. Verweij, PhD
Department of Developmental Psychology and EMGO Institute for Health and Care Research, VU University
Amsterdam, the Netherlands
MedicalResearch.com: What are the main findings of the study?
Dr. Verweij: We performed a twin study using over 10,000 adult Australian twins to determine the relative importance of genetic and environmental influences on individual differences in non-suicidal self-injury (NSSI) and suicidal ideation and their covariation.
We found that individuals that report self-harm are approximately eight times more likely to also report suicidal ideation. Results from the bivariate genetic model indicated that the substantial correlation between non-suicidal self-injury and suicidal ideation (r=0.49 for males and 0.61 for females) is largely explained by overlapping genetic factors: 62% and 76% for males and females, respectively. Overlapping residual influences, including nonshared environmental influences and measurement error, also explain part of the covariance between the two traits. These findings suggest that the two behaviors share similar biological underpinnings.
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