MedicalResearch.com Interview with:
Zanusso Gianluigi M.D.Ph.D.
Department of Neurosciences, Biomedicine and Movement Sciences
University of Verona
MedicalResearch.com: What is the background for this study? What are the main findings?
Response: To determine RT-QuIC assay sensitivity and specificity in cerebrospinal fluid and olfactory mucosa in a large group of patients with a clinical diagnosis of probable, possible or suspect Creutzfeldt–Jakob disease (CJD) and controls.
In these patients, RT-QuIC testing of CSF and olfactory mucosa provided a specificity and sensitivity of 100%.
A softer swab for olfactory mucosa sampling provided the same sensitivity as using a brush .