MedicalResearch.com Interview with: Prof. Alexander Binshtok PhD Cecile and Seymour Alpert Professor in Pain Research Hebrew University’s Faculty of Medicine and Center for Brain Sciences (ELSC) MedicalResearch.com: What is the background for this study? Response: Paracetamol (also known as acetaminophen) is one of the world’s most commonly used pain relievers and fever reducers, yet for decades, its precise biological mechanism has remained something of a mystery. Traditionally, scientists believed its analgesic effect stemmed from central nervous system activity—specifically through the action of its metabolite, AM404, on cannabinoid and TRPV1 receptors in the brain. (more…)