Author Interviews, Flu - Influenza, Pulmonary Disease, Stem Cells, University of Pennsylvania / 22.08.2019

MedicalResearch.com Interview with: Andrew E. Vaughan, PhD Assistant Professor, Biomedical Sciences School of Veterinary Medicine University of Pennsylvania MedicalResearch.com: What is the background for this study? What are the main findings? Response: Severe respiratory infections, including influenza, can progress to acute respiratory distress syndrome (ARDS), wherein barrier function and gas exchange are compromised. It’s a very life threatening scenario. This is due in part to loss of alveolar type 2 (surfactant producing) and type 1 cells (gas exchanging). Interestingly alveolar type 2 cells are also stem cells in the lung. We wondered whether transplant of these cells might aid in recovery from severe influenza infection, and sure enough, it did! (more…)