Author Interviews, Dermatology, JAMA / 08.09.2017 Interview with: Kaveri Korgavkar, MD Department of Dermatology Brown University Providence, Rhode Island What is the background for this study? What are the main findings? Response: Photodamage refers to premature skin aging from long-term UV exposure. Topical fluorouracil cream, typically used in the treatment of actinic keratosis, has been suggested for use in treating photodamage due to clinical and histological findings. However, in our ad hoc secondary analysis of a large randomized clinical trial, a standard course of topical fluorouracil did not result in detectable improvement of photodamage. (more…)