MedicalResearch.com Interview with:
Sung Kyun Park Sc.D. M.P.H.
Associate professor of epidemiology and environmental health sciences
University of Michigan School of Public Health
Ann Arbor, Michigan
MedicalResearch.com: What is the background for this study? What are the main findings?
Response: It is poorly understood that why some patients need more drugs to control high blood pressure than others. Resistant hypertension is that blood pressure is not controlled with 3 medications of different classes including diuretics or is required 4 or more medications of different classes for blood pressure controls. Genes, obesity, physical inactivity, high salt diet, pain medications may do something. Lead is a widespread environmental toxin that can influence high blood pressure. In this study, we examined whether long-term exposure to lead, measured as bone lead, is associated with the risk of resistant hypertension.
Bone lead offers a better method over blood lead measurement to discern long-term lead exposure and accumulation.
The main finding of our study is that low-level lead exposure, measured in the tibia (hard bone), is associated with higher risk of development of resistant hypertension in a cohort of patients diagnosed with hypertension. Continue reading