Author Interviews, Dermatology, JAMA, Microbiome / 19.01.2018
Atopic Dermatitis: Skin Microbiome Altered in Lesional and Non-Lesional Skin
MedicalResearch.com Interview with:
Maja-Lisa Clausen MD, Ph.D.-fellow
Department of Dermatology
Copenhagen University Hospital Bispebjerg
MedicalResearch.com: What is the background for this study?
Response: The human microbiome seems to play an important role in health and disease, by influencing host cells and contributing to host immunity. A balanced interplay between host cells and resident bacteria is important, and dysbiosis is linked to several diseases, including skin diseases like atopic dermatitis. Patients with atopic dermatitis suffer from frequent skin infections, and their skin microbiome is dominated by S. aureus. Frequent skin infections lead to frequent use of antibiotics, and with worldwide increase in resistant bacteria, a better understanding of the interplay between host and bacteria is paramount in order to develop new treatment strategies.
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