MedicalResearch.com Interview with:
Hariom Yadav, PhD
Assistant Professor, Molecular Medicine
Comprehensive Cancer Center
Center on Diabetes, Obesity, and Metabolism
Redox Biology & Medicine Ctr
Sticht Center on Aging
MedicalResearch.com: What is the background for this study? What are the main findings?
Response: Currently, the use of probiotics is increasing for health benefits of consumers, however the source of probiotics available in the market remains scarcely known. According to scientific community and regulatory standpoint, human-origin probiotics are highly recommended. Hence, we isolated these probiotics from baby diapers, because infant microbiome carries large number of beneficial bacteria.
In addition, we optimized our probiotics to produce higher amount of short-chain fatty acids (SCFAs; beneficial metabolites produced by the gut microbiome), because the levels of SCFAs decreases in several human diseases like obesity, diabetes, cancer, autoimmune and inflammatory bowel diseases. Hence, our probiotics can be used to bring back SCFAs levels and may benefit people suffering from these diseases.