MedicalResearch.com Interview with:
Harmony Reynolds, MD
Saul J. Farber Associate Professor of Medicine
NYU Langone Medical Center
MedicalResearch.com: What is the background for this study?
Response: Some patients with heart attack have open, rather than severely narrowed, coronary arteries when they have a heart attack. This type of heart attack, known as myocardial infarction with non-obstructive coronary arteries or MINOCA, can be caused by a number of different problems. Cardiac MRI is useful because it can help physicians to find the underlying cause of MINOCA.
MINOCA patients with ST elevation on the ECG are at higher risk of death than those without ST elevation but it is not known whether ST elevation correlates with any specific underlying cause of MINOCA.
MedicalResearch.com: What are the main findings?
Response: There was no difference in the findings on Cardiac MRI between those MINOCA patients with and without ST elevation. The MRI results were fairly evenly distributed between the different causes.
MedicalResearch.com: What should readers take away from your report?
Response: Additional testing is needed to find the underlying cause of MINOCA. ST elevation on the ECG is a risk factor for death but this is not because it points us toward any particular underlying cause of MINOCA.
MedicalResearch.com: What recommendations do you have for future research as a result of this study?
Response: We need prospective studies using additional imaging, like Cardiac MRI and intracoronary imaging (e.g., OCT and IVUS) in MINOCA patients with different ECG findings in order to understand why MINOCA occurs and how to treat it.
MedicalResearch.com: Is there anything else you would like to add?
Response: We are conducting a multi-center diagnostic study in MINOCA, funded by the American Heart Association.
MedicalResearch.com: Thank you for your contribution to the MedicalResearch.com community.
Citation: Abstract presented at the March 2017 AAC meeting
Session 1253 – Acute Coronary Syndromes, Diagnosis, Management and Outcomes
1253-348 / 348 – ST-Segment Elevation and Cardiac Magnetic Resonance Imaging Findings in Myocardial Infarction With Non-Obstructive Coronary Arteries
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March 18, 2017, 3:45 – 4:30 PM
Harmony R. Reynolds, Sivabaskari Pasupathy, Himali Gandhi, Rosanna Tavella, Leon Axel, John Beltrame, NYU School of Medicine, New York, NY, USA, University of Adelaide, Adelaide, Australia
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