13 Aug Fresh Donor Eggs Result In More Live Births Than Frozen

MedicalResearch.com Interview with:
Vitaly A Kushnir MD
The Center for Human Reproduction
New York, NY 10021

Medical Research: What is the background for this study? What are the main findings?

Dr. Kushnir: In January 2013, the American Society for Reproductive Medicine declared the technique of oocyte cryopreservation no longer experimental, although they body did call for further study.

Vitaly A. Kushnir, M.D., of the Center for Human Reproduction, and colleagues used 2013 data from 380 U.S fertility centers to compare live birth and cycle cancellation rates using either fresh or cryopreserved donor oocytes.

The study found roughly 20 percent of donor cycles used cryopreserved oocytes and 80 percent fresh oocytes. Of those embryos transferred, 56 percent that started as fresh oocytes resulted in live births compared to just 47 percent of those that started as cryopreserved oocytes.

Medical Research: What should clinicians and patients take away from your report?

Dr. Kushnir: So called “egg-freezing” has recently become commonplace and more often used for delaying parenthood for social reasons. It is important clinicians and patients know the associated risks of cryopreservation. In this study, it appears using fresh donor eggs results in a better outcome than those that have been earlier collected, frozen, and thawed.

Patients and clinicians need to evaluate their options carefully when making the decision between fresh and frozen donor eggs.

Medical Research: What recommendations do you have for future research as a result of this study?

Dr. Kushnir: The reason for this statistically-important difference in live birth rates is still unclear and was not a focus of the study. As cryopreservation becomes more and more the norm the authors hope the cause is quickly identified and mitigating measures put into place.

Citation:

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Vitaly A Kushnir MD (2015). Fresh Donor Eggs Result In More Live Births Than Frozen MedicalResearch.com

Vitaly A Kushnir MD (2015). Fresh Donor Eggs Result In More Live Births Than Frozen MedicalResearch.com

Last Updated on August 13, 2015 by Marie Benz MD FAAD