Author Interviews, Diabetes, Environmental Risks / 24.06.2024

MedicalResearch.com Interview with: Todd Hagobian, Ph.D. pronouns he/him/his Department Chair & Professor, Kinesiology and Public Health Cal Poly, San Luis Obispo, CA MedicalResearch.com: What is the background for this study? Response: Previous observational studies have shown that urinary BPA is related to Type 2 diabetes risk. Meaning, higher urinary BPA is related to an increased risk of Type 2 diabetes. However, no published study to date has determined whether several days of BPA administration (participants consume BPA) increases the risk of Type 2 diabetes. MedicalResearch.com: Where is bisphenol found?  Can exposure to bisphenol be limited in everyday life? Response:  BPA and other bisphenols are found in canned foods and plastics. BPA is one of the most widely used synthetic chemicals and we consume foods that are packed in this chemical. Most of BPA exposure comes from canned foods, and 93% of the US populations has detectable urine levels of BPA. We can limit BPA by reducing canned foods (or purchased BPA free cans) and plastic use. (more…)
Author Interviews, Environmental Risks, NYU, Pediatrics, Weight Research / 26.07.2019

MedicalResearch.com Interview with: Melanie Jacobson, PhD, MPH NYU School of Medicine New York, N.Y.  MedicalResearch.com: What is the background for this study? What are the main findings? Response: Our study was about exposure to bisphenols, which are synthetic chemicals found in aluminum can linings, plastics, thermal paper receipts and other consumer products, and their association with obesity among a nationally representative sample of US children and adolescents. We found that children who had greater levels of these chemicals in their urine were more likely to be obese compared with children with lower levels. (more…)
Author Interviews, Breast Cancer, Environmental Risks, Toxin Research / 05.04.2017

MedicalResearch.com Interview with: Sumi Dinda, PhD, NRP, IC. Associate Professor Biomedical Diagnostic and Therapeutic Sciences, School of Health Sciences and Adjunct Associate Professor Department of Biological Sciences School of Health Sciences Oakland University Rochester, MI 48309. MedicalResearch.com: What is the background for this study? What are the main findings? Response: Bisphenol-S (BPS), a substitute for bisphenol-A (BPA), has been suggested to be an endocrine disrupting compound interfering with normal hormonal activity. This bisphenol analogue is found in plastic substitutes, paper currency, and most products marked “BPA free.” Endocrine disrupting compounds interfere with the normal hormonal activity in the body. Bisphenols, specifically, disrupt the proper functioning of estrogen receptors, such as ERα causing interference with the normal activity of the hormone estrogen. Studies suggest BPS induces ERα pathways via its estrogen-mimicking properties in the body causing increased cell proliferation resulting in increased breast cancer risk. Despite the hope of a safer substitute, studies have shown that BPS exhibits similar estrogenic activity compared to its analogue BPA, due to their structural commonalities. BRCA1 is a commonly mutated gene in breast cancer; therefore, it is also important to study the effects of BPS on the expression of this protein. The potency of the endocrine disrupting abilities of BPS compared to BPA could show whether BPS is a suitable alternative to BPA in many everyday products. The results of this study may contribute to the understanding of the relationship between ERα, BRCA1 expression and Bisphenol-S in breast cancer treatment and prevention. (more…)