Skin Irritants Increase Risk of Urinary Tract Infections

Steve J. Hodges MD Associate Professor, Department of Urology Wake Forest University School of Medicine Medical Center Blvd, Winston-Salem, NCMedicalResearch.com Interview with:
Steve J. Hodges MD
Associate Professor, Department of Urology
Wake Forest University School of Medicine
Medical Center Blvd, Winston-Salem, NC

Medical Research: What are the main findings of this study?

Dr. Hodges: The main findings of this study were that skin irritants (typically urine) may cause vulvitis in prepubertal girls, which leads to an alteration of their perineal microbiome, with increased colonization by uropathogenic bacteria, increasing the risk of UTI.
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Overactive Bladder: Use of Antimuscarinics

MedicalResearch.com Interview with:

Kirill Kosilov
Far Eastern Federal University
Department of Neurourology-Urodynamics, Primorsky Regional Diagnostic Center, Vladivostok, Russian Federation

MedicalResearch.com What are the main findings of the study?

Answer: Our study in a group of elderly patients showed that the combination of antimuscarinic drugs in a dosage which is higher than the usual recommended one is an effective treatment option for patients with OAB in those cases where treatment with one antimuscarinic drug was poorly effective. Side effects occurred almost equally in patients treated with only one antimuscarinic drug compared to the combined dosage.
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