Alzheimer's - Dementia, Author Interviews, Cognitive Issues / 28.03.2020
Does Aspirin Reduce the Risk of Alzheimer’s Disease?
MedicalResearch.com Interview with:
Joanne Ryan, PhD
Senior Research Fellow, ASPREE
From the School of Public Health and Preventive Medicine
Monash University
Melbourne, Australia
MedicalResearch.com: What is the background for this study?
Response: Aspirin is a commonly used drug known to reduce inflammation, and prevent blood clotting (antiplatelet) - which is why it is commonly used in secondary prevention in individuals with established cardiovascular disease.
Inflammation is thought to be a central mechanism in Alzheimer's disease, implicated in the neuropathological cascade leading to the development of dementia and other forms of dementia.
Cardiovascular risk factors and stroke are both associated with cognitive decline and an increased risk of dementia.
This formed the basis of the hypothesis that aspirin could be beneficial in helping to reduce cognitive decline and the occurrence of Alzheimer's Disease.
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