MedicalResearch.com Interview with: Rick Woychik, Ph.D. Director of the National Toxicology Program Director of the National Institute of Environmental Health Sciences Principal Investigator Mammalian Genome Research Group Division for Intramural Research at NIEHS MedicalResearch.com: What is the background for this study? Response: Since 1945, the use of fluoride has been a successful public health initiative for reducing dental cavities and improving general oral health of adults and children. There is a concern, however, that some pregnant women and children may be getting more fluoride than they need because they now get fluoride from many sources including treated public water, water-added foods and beverages, teas, toothpaste, floss, and mouthwash, and the combined total intake of fluoride may exceed safe amounts.   Therefore, the National Toxicology Program (NTP) conducted a systematic review of the published scientific literature on the association between fluoride exposure and neurodevelopment and cognition. The NTP released their findings in a State of the Science Monograph on August 21, 2024, and posted to the NTP website. A corresponding meta-analysis on children’s IQ has been accepted by a scientific journal for publication later in 2024. The NTP started this work in 2016. As with all research documents intended for publication, the NTP fluoride monograph and meta-analysis underwent rigorous scientific evaluation.  The evaluation process has involved many steps. The draft fluoride monograph received significant critical feedback during peer-review by the National Academies of Science, Engineering and Medicine (NASEM), from other external experts, and from experts in several federal health agencies.  After modifications were made, additional evaluation following a rigorous scientific framework was conducted by subject matter experts organized by the NTP Board of Scientific Counselors. I am very pleased that this document is now complete and available for reference. Since fluoride is such an important topic to the public and to public health officials, it was imperative that we made every effort to get the science right. I commend the report authors, the NTP Board of Scientific Counselors, and countless subject matter experts who participated in this evaluation. The monograph represents a thorough review of the data, and the various interpretations of the data, to accurately reflect what we know and where additional research is needed. (more…)