fungal infections Tag

05 Jun

Posted at 11:49h in Author Interviews, Infections, Pediatrics
MedicalResearch.com Interview with: [caption id="attachment_54456" align="alignleft" width="133"] Dr. Vlahovic[/caption] Tracey Vlahovic  DPM, FFPM, FCPS Clinical Professor, Department of Podiatric Medicine Stanley and Pearl Landau Faculty Fellow Adjunct Professor, Department of Microbiology, Temple University School of Medicine On Behalf of Ortho Dermatologics MedicalResearch.com: What is the background for this study? Response: JUBLIA® was first approved in 2014 for people 18 years of age and older. However, more and more children are being diagnosed with onychomycosis, so the goal of the study was to determine the safety and efficacy of Jublia in this patient population.

21 Jul

Posted at 00:12h in Author Interviews, Biomarkers, Infections
MedicalResearch.com Interview with: [caption id="attachment_43348" align="alignleft" width="200"]David K. Hong, M.D. VP Medical Affairs and Clinical Development at Karius Dr. Hong[/caption] David K. Hong, M.D. VP Medical Affairs and Clinical Development at Karius MedicalResearch.com: What is the background for this study? What are the main findings?  Response: Invasive fungal infections (IFI) are a cause of significant mortality and morbidity in immunocompromised patients. The diagnosis of IFIs is challenging, and often requires an invasive biopsy in order to identify the causal pathogen. There is a need for non-invasive methods of fungal identification to help guide targeted anti-fungal therapy.

22 Nov

Posted at 20:49h in Author Interviews, Dermatology, Infections
MedicalResearch.com Interview with: [caption id="attachment_29900" align="alignleft" width="160"]Adam Friedman, MD, FAAD Associate Professor of Dermatology Residency Program Director Director of Translational Research Department of Dermatology George Washington School of Medicine and Health Sciences Dr. Adam Friedman[/caption] Adam Friedman, MD, FAAD Associate Professor of Dermatology Residency Program Director Director of Translational Research Department of Dermatology George Washington School of Medicine and Health Sciences MedicalResearch.com: What is the background for this study? What are the main findings? Response: This study was developed out of a session I and my colleague, Neal Bhatia, held at the 2016 Orlando Dermatology Aesthetic and Clinical Conference. As an interactive session which had the audience answer whether they clinically thought an image was representative of a fungal skin infection or not, we collected audience responses and were impressed by how even dermatologists struggle with making this diagnosis clinically. This is not so surprising given the protean nature and diverse presentations of these infections, not to mention the many mimics which are not due to infection. Only one of the thirteen images shown was appropriately diagnosed by 90% of the audience. This highlights that the importance of using bedside diagnostic techniques such as KOH preps and culture to identify underlying cause in order to appropriately use the right therapy for the right condition.

08 Nov

Posted at 00:50h in Author Interviews, CDC, Infections
MedicalResearch.com Interview with: Dr. Snigdha Vallabhaneni Medical epidemiologist Mycotic Diseases Branch CDC MedicalResearch.com: What is the background for this study? What are the main findings? Response: This report is the first to describe U.S. cases of C. auris infection. C. auris is often resistant to antifungal drugs and tends to occur in hospitalized patients. In June 2016, CDC issued a clinical alert describing the global emergence of C. auris and requesting that laboratories report C. auris cases and send patient samples to state and local health departments and CDC. Since then, CDC has been investigating reports of C. auris with several state and local health departments. Seven of the cases occurred between May 2013 and August 2016 and are described in this report. Among the seven cases detailed in the report, patients with C. auris were reported in four states: New York, Illinois, Maryland and New Jersey. All of the patients had serious underlying medical conditions and had been hospitalized an average of 18 days when C. auris was identified. Four of the patients died; it is unclear whether the deaths were associated with C. auris infection or underlying health conditions.