MedicalResearch.com Interview with:
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Dr. Zhe-Xue Quan[/caption]
Zhe-Xue Quan, PhD
Ministry of Education Key Laboratory for Biodiversity Science and Ecological Engineering
Institute of Biodiversity Science
School of Life Sciences, Fudan University
Shanghai, China
MedicalResearch.com: What is the background for this study? What are the main findings?
Response: The maturation of skin microbial communities during childhood is important for the skin health of children and development of the immune system into adulthood. This necessitates a better characterization of the environmental and genetic factors influencing these microbiome dynamics.
We investigated the skin microbiota of children (158 subjects between 1 and 10 years old) and their mothers using 16S rRNA gene amplicon sequencing. Sample location and age were the primary factors determining a child’s skin bacterial composition. Relative abundances of Streptococcus and Granulicatella were negatively correlated with age, and the alpha diversity at all body sites examined increased during the first 10 years of life, especially on the face. The facial bacterial composition of 10-year-old children was strongly associated with delivery mode at birth.