Alzheimer's - Dementia, Author Interviews, Genetic Research, JAMA, Karolinski Institute / 24.03.2026
Karolinska Institutet Study Finds APOE Genotype Influences Link Between Red Meat Consumption and Cognitive Decline
[caption id="attachment_72900" align="alignleft" width="200"] Jakob Norgren, Ph.D.[/caption]
MedicalResearch.com Interview with:
Jakob Norgren | PhD, Postdoctoral Researcher
Department of Neurobiology, Care Sciences and Society (NVS) | Karolinska Institutet
Division of Clinical Geriatrics | Center for Alzheimer Research
Huddinge, Sweden
MedicalResearch.com: What is the background for this study?
Response: This study tested the hypothesis that people with APOE 3/4 and 4/4 would have a reduced risk of cognitive decline and dementia with higher meat intake, based on the fact that APOE4 is the evolutionarily oldest variant of the APOE gene and may have arisen during a period when our evolutionary ancestors ate a more animal-based diet.
Jakob Norgren, Ph.D.[/caption]
MedicalResearch.com Interview with:
Jakob Norgren | PhD, Postdoctoral Researcher
Department of Neurobiology, Care Sciences and Society (NVS) | Karolinska Institutet
Division of Clinical Geriatrics | Center for Alzheimer Research
Huddinge, Sweden
MedicalResearch.com: What is the background for this study?
Response: This study tested the hypothesis that people with APOE 3/4 and 4/4 would have a reduced risk of cognitive decline and dementia with higher meat intake, based on the fact that APOE4 is the evolutionarily oldest variant of the APOE gene and may have arisen during a period when our evolutionary ancestors ate a more animal-based diet.