Low Vitamin D Linked To Increase Risk of Orthostatic Hypotension

MedicalResearch.com Interview with:
Dr. Nicola Veronese
University of Padova
Department of Medicine – DIMED, Geriatrics Division
Padova, Italy

MedicalResearch.com: What is the background for this study? What are the main findings?

Response: In the last 5 years, some studies investigated the possible association between hypovitaminosis D and orthostatic hypotension. However, all these studies were cross-sectional,  not disentangling if hypovitaminosis D precedes or follows orthostatic hypotension. In our work, we reported that low vitamin D at baseline predict the onset of orthostatic hypotension at follow-up in older people. This association was stronger in women than in men.

MedicalResearch.com: What should readers take away from your report?

Response: Our study confirms a potential role of hypovitaminosis D in the pathogenesis of orthostatic hypotension. Due to the importance and the frequency of orthostatic hypotension in the elderly, to know if hypovitaminosis D could be considered a risk factor for this condition could be of importance.

MedicalResearch.com: What recommendations do you have for future research as a result of this study?

Response: Due to the observational nature of our work, it is not possible to say if reversing hypovitaminosis D could improve orthostatic hypotension in older people. To the best of our knowledge, only one study assessed this topic with not significant results. However, this was a secondary analysis of a larger trial and future trials are needed to verify the effect of vitamin D supplementation on orthostatic hypotension.

MedicalResearch.com: Thank you for your contribution to the MedicalResearch.com community.


Hypovitaminosis D Predicts the Onset of Orthostatic Hypotension in Older Adults
Veronese, Nicola et al.
Journal of the American Society of Hypertension , Volume 0 , Issue 0 ,

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Last Updated on July 8, 2016 by Marie Benz MD FAAD