14 Mar Recurrent Ischemia Events Vary By Type of Presenting Cardiac Disease
MedicalResearch.com Interview with:
Dr. Thomas Pilgrim
Prof. Dr. Thomas Pilgrim
Inselspital
Berne Switzerland
Medical Research: What is the background for this study?
Dr. Pilgrim: Long-term prognostic implications of different clinical manifestations of coronary artery disease are insufficiently understood at this time. A time variable pattern of recurrent events following PCI for STEMI, Non-STE-ACS or stable ischemic heart disease may have important implications for medical management and secondary prevention.
Medical Research:? What are the main findings?
Dr. Pilgrim: In our analysis, we found a differential in timing of ischemic events after PCI according to presentation with STEMI, NSTE-ACS, or stable ischemic heart disease, respectively. While patients with NSTE-ACS were at increased risk of death at any time after PCI as compared to patients with stable ischemic heart disease, patients with STEMI had an increased risk during the first 30 days after PCI but not thereafter compared to patients with stable ischemic heart disease.
Medical Research: What should clinicians and patients take away from your report?
Dr. Pilgrim: Different manifestations of coronary artery disease are associated with different time-variable patterns of adverse ischemic events. While patients with STEMI are known to have a high risk of adverse events in the early period after myocardial infarction, the long-term risk of patients with NSTE-ACS may often be neglected and needs to be addressed with effective secondary prevention.
Medical Research: What recommendations do you have for future research as a result of this study?
Response: Different factors involved in progression of coronary artery disease and recurrence of ischemic events need to be investigated in more detail.
Citation:
Risk and timing of recurrent ischemic events among patients with stable ischemic heart disease, non–ST-segment elevation acute coronary syndrome, and ST-segment elevation myocardial infarction
Published Online:February 22, 2016
DOI: http://dx.doi.org/10.1016/j.ahj.2016.01.021
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Recurrent Ischemia Events Vary By Type of Presenting Cardiac Disease (2016). Recurrent Ischemia Events Vary By Type of Presenting Cardiac Disease MedicalResearch.com
Last Updated on March 14, 2016 by Marie Benz MD FAAD