Psoriasis: Increased Cardiovascular Disease Risk May Limited To Patients With Family History

MedicalResearch.com Interview with:

Alexander Egeberg, MD PhD National Allergy Research Centre, Departments of Dermato-Allergology and Cardiology Herlev and Gentofte University Hospital, University of Copenhagen Hellerup, Denmark

Dr. Alexander Egeberg

Alexander Egeberg, MD PhD
Gentofte Hospital
Department of Dermatology and Allergy
Denmark

MedicalResearch.com: What is the background for this study? What are the main findings?

Dr. Egeberg: While psoriasis has been associated with an increased risk of cardiovascular disease (CVD), studies have generally neglected to adjust for family history of CVD which is a well-established cardiovascular risk factor.

In a population-based study of young patients with psoriasis, we found an increased risk of CVD only in patients with a positive family history of CVD but not in those patients that did not have a positive family history.

MedicalResearch.com: What should readers take away from your report?

Dr. Egeberg: It appears that a family history of cardiovascular disease may be a primary determining factor of future CVD in patients with psoriasis. Whether this is due to a genetic link, or if this is the results of unhealthy familial lifestyle factors requires further study.

MedicalResearch.com: What recommendations do you have for future research as a result of this study?

Dr. Egeberg: Studies assessing cardiovascular disease risk in patients with psoriasis should include family history as a potential confounding factor.

MedicalResearch.com: Thank you for your contribution to the MedicalResearch.com community.

Citation:
Family history predicts major adverse cardiovascular events (MACE) in young adults with psoriasis
Egeberg, Alexander et al.
Journal of the American Academy of Dermatology
Published Online: June 07, 2016

DOI: http://dx.doi.org/10.1016/j.jaad.2016.02.1227

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Last Updated on June 9, 2016 by Marie Benz MD FAAD