Michelle Androulakis, MD, MS, FAHS Chief of Neurology WJB Dorn VA Medical Center and Faculty at University of South Carolina. Columbia, SC

Dive Deep Into Migraine’s Link to Increased Stroke Incidence

MedicalResearch.com Interview with

Michelle Androulakis, MD, MS, FAHS Chief of Neurology WJB Dorn VA Medical Center and Faculty at University of South Carolina. Columbia, SC

Dr. Androulakis

Michelle Androulakis, MD, MS, FAHS
Chief of Neurology
WJB Dorn VA Medical Center and
Faculty at University of South Carolina.
Columbia, SC

MedicalResearch.com: What is the background for this study? What are the main findings? 

Response: Even though Migraine with aura was associated with an increased risk of ischemic stroke in the Atherosclerosis Risk in Communities study (ARIC), our post-hoc showed unexpected results that onset of such migraines before age 50 years is not associated with such risk. Instead, later onset of migraine with aura after age of 50 was linked with a higher risk of ischemic stroke.

Total of 447 migraineurs with aura (MA) and 1128 migraineurs without aura (MO) among 11,592 participants were included in the analysis. There was a two-fold increased risk of ischemic stroke when the age of migraineurs with aura onset was 50 years or older as compared with no headache participants, MO was not associated with increased stroke risk regardless of age of onset. 

MedicalResearch.com: What should readers take away from your report?

Response: Further prospective study to investigate the link between migraine symptoms onset and frequency of exposure to migraineurs with aura and ischemic stroke risk are warranted. 

MedicalResearch.com: What recommendations do you have for future research as a result of this work? 

Response: Further prospective study to investigate the link between migraine symptoms onset and frequency of exposure to migraineurs with aura and ischemic stroke risk are warranted.

Disclosures: I have no disclosures and this study was not supported financially by any federal or private funds.

The Atherosclerosis Risk in Communities study has been funded with federal funds from national Heart, lung and blood institute, NIH, DHH.

Citation:

Michelle Androulakis, Souvik Sen, Nishanth Kodumuri, Tianming Zhang, John Grego, Wayne Rosamond, Rebecca F. Gottesman, Eyal Shahar, B. Lee Peterlin. Migraine Age of Onset and Association With Ischemic Stroke in Late Life: 20 Years Follow-Up in ARIC. Headache: The Journal of Head and Face Pain, 2019; DOI: 10.1111/head.13468

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Last Updated on February 4, 2019 by Marie Benz MD FAAD