Gastric Bypass: Half of Diabetic Patients In Remission 12 Years After Surgery Interview with:
Ted Adams PhD
Adjunct Professor, Internal Medicine
Adjunct Associate Professor, Nutrition & Integrative Physiology
The University of Utah Why did you decide to conduct this study?

Response: The primary aim of the study was to determine the clinical outcomes in patients who underwent gastric bypass surgery.

As NIDDK/NIH continued to fund the study, the aim was extended to determining the durability) long-term outcomes) of gastric bypass surgery when compared to non-surgical, severely obese patients. Were you surprised by the findings? Why or why not?

Response: Because we have previously published the clinical results at two and six year follow-up periods, we hoped to see similar favorable outcomes at 12 years.

The fact that the mean 12-year percent weight loss from baseline was very similar to that measured at 6 years follow-up was somewhat of a surprise. We were anxious to see what percentage of gastric bypass patients who had diabetes prior to their surgery were in remission (diabetes remission) at 12 years. The finding of 51% was encouraging. Do you plan to do any additional follow-up studies?

Response: We are hopeful that we can obtain continued funding to follow the surgical and non-surgical participants. We have appreciated the great support the participants have given to this study. Thank you for your contribution to the community.

Citation: NEJM

Weight and Metabolic Outcomes 12 Years after Gastric Bypass

Ted D. Adams, Ph.D., M.P.H., Lance E. Davidson, Ph.D., Sheldon E. Litwin, M.D., Jaewhan Kim, Ph.D., Ronette L. Kolotkin, Ph.D., M. Nazeem Nanjee, Ph.D., Jonathan M. Gutierrez, B.S., Sara J. Frogley, M.B.A., Anna R. Ibele, M.D., Eliot A. Brinton, M.D., Paul N. Hopkins, M.D., M.S.P.H., Rodrick McKinlay, M.D., Steven C. Simper, M.D., and Steven C. Hunt, Ph.D.

N Engl J Med 2017; 377:1143-1155 September 21, 2017DOI: 10.1056/NEJMoa1700459

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Last Updated on September 20, 2017 by Marie Benz MD FAAD