Psoriasis: Increased Cardiovascular Disease Risk May Limited To Patients With Family History Interview with:

Alexander Egeberg, MD PhD National Allergy Research Centre, Departments of Dermato-Allergology and Cardiology Herlev and Gentofte University Hospital, University of Copenhagen Hellerup, Denmark

Dr. Alexander Egeberg

Alexander Egeberg, MD PhD
Gentofte Hospital
Department of Dermatology and Allergy
Denmark What is the background for this study? What are the main findings?

Dr. Egeberg: While psoriasis has been associated with an increased risk of cardiovascular disease (CVD), studies have generally neglected to adjust for family history of CVD which is a well-established cardiovascular risk factor.

In a population-based study of young patients with psoriasis, we found an increased risk of CVD only in patients with a positive family history of CVD but not in those patients that did not have a positive family history. What should readers take away from your report?

Dr. Egeberg: It appears that a family history of cardiovascular disease may be a primary determining factor of future CVD in patients with psoriasis. Whether this is due to a genetic link, or if this is the results of unhealthy familial lifestyle factors requires further study. What recommendations do you have for future research as a result of this study?

Dr. Egeberg: Studies assessing cardiovascular disease risk in patients with psoriasis should include family history as a potential confounding factor. Thank you for your contribution to the community.

Family history predicts major adverse cardiovascular events (MACE) in young adults with psoriasis
Egeberg, Alexander et al.
Journal of the American Academy of Dermatology
Published Online: June 07, 2016


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Last Updated on June 9, 2016 by Marie Benz MD FAAD