25 Feb Larger Grafts Do Better For Biological Hip Joint Replacement

Posted at 18:33h in Author Interviews, Orthopedics, Transplantation by

MedicalResearch.com Interview with:

Dr. Brett Crist MD FACS Associate Professor of Orthopaedic Surgery Co-Chief, Orthopaedic Trauma Division Associate Director, Joint Preservation Surgery Director, Trauma Orthopaedic Fellowship School of Medicine University of Missouri Health

Dr. Brett Crist

Dr. Brett Crist MD FACS
Associate Professor of Orthopaedic Surgery
Co-Chief, Orthopaedic Trauma Division
Associate Director, Joint Preservation Surgery
Director, Trauma Orthopaedic Fellowship
School of Medicine
University of Missouri Health 

Medical Research: What is the background for this study? What are the main findings?

Dr. Crist: Some young patients have bone and/or cartilage problems on the femoral head due to disease or injury.  Resurfacing the femoral head with donated bone and cartilage tissue is often a better option for these young patients with active lifestyles, who would otherwise require an artificial joint that would limit their activities and eventually wear out. However, there is no standard method for implantation. Our study provides initial clinical evidence that larger, size-matched grafts have the potential to improve outcomes when resurfacing cartilage defects of the femoral head in the hip joint.

Medical Research: What should clinicians and patients take away from your report?

Dr. Crist: When doing osteoarticular allografts of the femoral head, it appears that large grafts actually do better, and that this is a viable option for people.

Medical Research: What recommendations do you have for future research as a result of this study?

Dr. Crist: The goal is to obtain prospective data on human patients showing the effectiveness of these large osteoarticular femoral head grafts. 

Medical Research: Is there anything else you would like to add?

Dr. Crist: We felt that the large grafts would do better, but we were surprised that the small grafts (current standard of care) didn’t make it to the six month postoperative examination.  We thought the smaller grafts would do better than that. This study emphasizes that the smaller grafts are more likely to fail.

Citation:

“Optimizing Femoral-head Osteochondral Allograft Transplantation in a Preclinical Model,” recently was published in the Journal of Orthopaedic Translation.

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Dr. Brett Crist MD FACS (2016). Larger Grafts Do Better For Biological Hip Joint Replacement 

Last Updated on February 25, 2016 by Marie Benz MD FAAD

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