20 Dec Mild Cognitive Impairment: Progression to Dementia Risk

MedicalResearch.com Interview with:
Dr. Ronald C. Petersen M.D., Ph.D.
Division of Epidemiology
Department of Health Sciences Research; Department of Neurology
Mayo Clinic, Rochester, MN

MedicalResearch.com: What are the main findings of the study?

Dr. Petersen: The diagnosis of mild cognitive impairment increases the likelihood of developing dementia.
MedicalResearch.com: Were any of the findings unexpected?

Dr. Petersen: Even in those subjects diagnosed with MCI who return to normal on a subsequent occasion still have an increased risk of developing dementia.

MedicalResearch.com: What should clinicians and patients take away from your report?

Dr. Petersen: Mild cognitive impairment is important to recognize to determine if any causes might be treatable and to plan for the future.

Dr. Petersen: We need to know if biomarkers will help sort out who will progress and who will not.

Citation:

Higher risk of progression to dementia in mild cognitive impairment cases who revert to normal

Rosebud O. Roberts, MB, ChB, David S. Knopman, MD, Michelle M. Mielke, PhD, Ruth H. Cha, MS, V. Shane Pankratz, PhD, Teresa J.H. Christianson, BSc, E. Geda, MD, MSc, Bradley F. Boeve, MD, Robert J. Ivnik, PhD, LP, Eric G. Tangalos, MD, Walter A. Rocca, MD, MPH and Ronald C. Petersen, MD, PhD

Published online before print December 18, 2013, doi: 10.1212/WNL
Neurology 10.1212/WNL.0000000000000055

Last Updated on March 19, 2014 by Marie Benz MD FAAD