Author Interviews, COVID -19 Coronavirus, JNCI, Johns Hopkins, Respiratory, Vaccine Studies / 22.04.2021 Interview with: Joel N. Blankson, MD, PhD Department of Infectious Diseases Associate Professor Cellular and Molecular Medicine Program Johns Hopkins What is the background for this study? Which vaccines did you evaluate? Response: Prior studies from several groups including our own have found T cell cross-recognition of peptides from SARS-CoV-2 and the common cold coronaviruses. We asked whether as a result of this cross-reactivity, immunization with the SARS-CoV-2 vaccine would also enhance T cell responses to the common cold coronaviruses. Prior studies also suggested that antibodies elicited from the mRNA vaccines had a reduced ability to neutralize the emerging variants of concern. Most of the study participants had received the Pfizer vaccine, but a few had received the Moderna vaccine. (more…)