Author Interviews, Cancer Research, Gastrointestinal Disease / 20.05.2022

MedicalResearch.com Interview with: Bashar J. Qumseya, MD, MPH, FASGE Associate Professor of Medicine Chief of Endoscopy University of Florida, Gainesville  MedicalResearch.com:  What is the background for this study?  What are the main findings? Response: Barrett’s esophagus (BE), is a premalignant condition that can lead to esophageal cancer (called esophageal adenocarcinoma). Both diseases have historically been thought of as diseases of elderly white males. While both diseases have been on the rise in the elderly population, we noted that some cancers are becoming more common at younger ages. We wanted to see if the prevalence of BE and EC are increasing at younger ages.  We aimed to assess the prevalence of BE in and EAC based on age group in a large database of over 5 million patients.  (more…)
Author Interviews, Gastrointestinal Disease, Transplantation / 19.05.2022

MedicalResearch.com Interview with: Karn Wijarnpreecha, MD, MPH Lead researcher of the study Transplant Hepatology Fellow University of Michigan MedicalResearch.com:  What is the background for this study?  Response: Nonalcoholic fatty liver disease (NAFLD) can develop in persons who are not overweight or obese (“lean person with NAFLD”) and approximately 10-20% of NAFLD were lean. NAFLD is a multisystem diseases that associated with cardiovascular diseases, metabolic diseases (diabetes, hypertension, and dyslipidemia), or chronic kidney disease. Whether lean persons with NAFLD have lower prevalence of cirrhosis, CVD, CKD than non-lean persons with NAFLD remains inconclusive. (more…)
Author Interviews, Gender Differences, Pancreatic, Race/Ethnic Diversity / 23.05.2021

MedicalResearch.com Interview with: Kelly Herremans, MD Lead researcher on the study Surgical research fellow University of Florida College of Medicine Gainesville MedicalResearch.com: What is the background for this study? Response: Pancreatic cancer is a deadly malignancy with an estimated 5-year survival rate of only 9%. Significant racial and ethnic disparities exist in pancreatic cancer. Underrepresentation in the clinical trials that determine safety and efficacy may contribute to these disparate outcomes. (more…)
Author Interviews, Diabetes, Gastrointestinal Disease, Weight Research / 16.05.2021

MedicalResearch.com Interview with: Anna Carolina Hoff, MD Lead researcher on the study Founder and Clinical Director Angioskope Brazil São José dos Campos  MedicalResearch.com: What is the background for this study? Response: Obesity is a chronic disease that has become a global pandemic, and its prevalence continues to increase. Overweight (Body Mass Index (BMI) ≥ 27 kg/m2) and obesity (BMI ≥ 30kg/m2) lead to numerous clinical comorbidities, including metabolic, cardiovascular, oncologic, and mental health disorders. It is challenging to achieve significant and sustained weight loss with diet and lifestyle modification alone. Additionally, a reversal of obesity-related co-morbidities and improvement in quality of life entails a percent total body weight loss (%TBWL) of between 5-10%, which is rarely achieved with medications alone. The Endoscopic Sleeve Gastroplasty (ESG) results in a %TBWL between 14.6%-19.7% at 18-24 months,  and improvements in systolic blood pressure (SBP), HbA1c, and dyslipidemia at 12 months. (more…)