Weaning To Hydrolyzed Infant Formula Did Not Reduce Risk of Type 1 Diabetes

MedicalResearch.com Interview with:
“Baby Bottle” by brokinhrt2 is licensed under CC BY 2.0Mikael Knip, MD, PhD

Professor of Pediatrics
TRIGR PI 

MedicalResearch.com: What is the background for this study? What are the main findings?

Response: Experimental studies have indicated that the avoidance of early exposure to cow’s milk proteins reduces the cumulative incidence of autoimmune diabetes in animal models of human type 1 diabetes, e.g. BB rats and NOD mice. Epidemiological studies in humans have suggested that there may be a link between type 1 diabetes and short breastfeeding or early introduction of infant formulas. All regular infant formulas contain intact cow’s milk proteins.

The main finding was that weaning to an extensively hydrolyzed formula did not reduce the cumulative incidence of Type 1 diabetes in at-risk children by the mean age of 11 years.

The extensively hydrolyzed formula did not contain any intact cow’s milk proteins but only small peptides (maximal size 2000 daltons).

Continue reading