Author Interviews, Brigham & Women's - Harvard, Fertility, Technology / 16.09.2020 Interview with: Hadi Shafiee, PhD Assistant Professor, Harvard Medical School Brigham and Women's Hospital Department of Medicine What is the background for this study? What are some of the characteristics that AI uses to identify blastocysts witha better chance of successful implantation? Response: In-vitro fertilization (IVF), while a solution to many infertile couples is still extremely inefficient with a success rate of nearly 30% and is both mentally, physically, and economically taxing to patients. The IVF process involves the insemination of eggs and the culture of embryos externally in a fertility lab before transferring the developed embryo to the mother. A major challenge in the field is deciding on the embryos that need to be transferred during IVF, such that chances of a healthy birth are maximal and any complications for both mother and child are minimal. Currently, the tools available to embryologists when making such are extremely limited and expensive, and thus, most embryologists are required to make these life-altering decisions using only their observational skills and expertise. In such scenarios, their decision-making process is extremely subjective and tends to be variable. (more…)
Author Interviews, Fertility, Heart Disease, OBGYNE, Pediatrics / 30.11.2017 Interview with: “2010 Nobel Prize in Medicine - development of the in vitro fertilization procedure” by Solis Invicti is licensed under CC BY 2.0 Paolo Cavoretto MD PhD San Raffaele Scientific Centre Obstetrics and Gynaecology Department Milan Italy What is the background for this study? Response: Congenital heart defects (CHD) are the most common forms of congenital disorders and a relevant cause of perinatal morbidity and mortality involving about 0.8% of pregnancies. IVF pregnancies are very common nowadays with increasing rates in the developed countries worldwide. There is no consensus in current practice guidelines whether IVF/ICSI conception represents an indication for performing a fetal echocardiogram according to different eminent scientific societies due to differences in the estimations of the risk for CHD in the available literature. (more…)