Mesothelioma, Ovarian Cancer / 08.10.2024

Mesothelioma, a rare and aggressive cancer, has long challenged medical professionals with its resistance to traditional treatments. As patients and doctors seek more effective options, immunotherapy emerges as a beacon of hope. This innovative approach harnesses the body's immune system to combat cancer cells, offering new possibilities for those affected by this devastating disease. While conventional therapies often fall short, immunotherapy presents a paradigm shift in mesothelioma treatment. By exploring these cutting-edge techniques, researchers and oncologists aim to improve patient outcomes and quality of life.

Understanding Mesothelioma

What is Mesothelioma?

Mesothelioma is a malignant tumor that develops in the lining of the lungs, chest wall, or abdomen. Primarily caused by asbestos exposure, this cancer often takes decades to manifest after initial contact with the harmful substance. Symptoms may include chest pain, persistent cough, and shortness of breath, making early diagnosis challenging. (more…)
AACR, Author Interviews, Cancer Research, Genetic Research, NIH / 23.04.2021

MedicalResearch.com Interview with: Nishanth Ulhas Nair, Ph.D. Affiliation: Staff Scientist at Cancer Data Science Laboratory, Center for Cancer Research National Cancer Institute (NCI), National Institutes of Health (NIH) Bethesda, Maryland, USA. Date: April 22, 2021 Dr. Raffit Hassan and Dr. Eytan Ruppin at the National Cancer Institute (NCI) are the senior authors of this study.  MedicalResearch.com: What is the background for this study? Response: Malignant mesothelioma is an aggressive cancer with limited treatment options and poor prognosis. An in-depth knowledge of genetic, transcriptomic and immunogenic events involved in mesothelioma is critical for successful development of prognostics and therapeutic modalities. In this study we aim to address this by exploring a new large scale patient tumor dataset of 122 mesothelioma patients, called NCI mesothelioma patient data, along with their genomic, transcriptomic, and phenotypic information. Unlike previous large-scale studies which have been focused on malignant pleural mesothelioma patients, our dataset contains an approximately equal representation of malignant pleural and peritoneal mesothelioma patients which allows to identify any differences between them. (more…)