Alzheimer's - Dementia, Author Interviews, Nutrition / 26.11.2022

MedicalResearch.com Interview with: Thomas M Holland, MD, MS Assistant Professor Rush Institute for Health Aging Rush College of Medicine & Rush College of Health Sciences https://www.rushu.rush.edu/faculty/thomas-m-holland-md-ms MedicalResearch.com: What is the background for this study? Response: My late mentor Martha Clare Morris, ScD had published a manuscript investigating leafy green intake, and the nutrients found therein, and cognition. I wanted to take this thought a step further and investigate the potential association bioactives, found in vegetables, like leafy greens, has to cognition. Further, this is a continuation of the research I published in the green journal in 2020 associating flavonols to incident Alzheimer’s dementia. This study extends the understanding that flavonols are not only beneficial for the most detrimental outcome of Alzheimer’s dementia (in decreasing the risk), but also advantageous in mitigating components of the, clinical syndrome i.e. decreasing the rate of cognitive decline. (more…)
Author Interviews, COVID -19 Coronavirus, Critical Care - Intensive Care - ICUs, Lancet, Pulmonary Disease / 26.08.2021

MedicalResearch.com Interview with: Jie Li, PhD, RRT, RRT-ACCS, RRT-NPS, FAARC Department of Cardiopulmonary Sciences Division of Respiratory Care Rush University, Chicago MedicalResearch.com: What is the background for this study? Response: Prone positioning has been shown to improve oxygenation and reduce mortality in intubated patients with acute respiratory distress syndrome (ARDS), as placing patients on their stomachs can help open alveoli and reduce ventilation to perfusion mismatch. At early pandemic, clinicians tried prone positioning for non-intubated patients with COVID-19 and found improvement in oxygenation. However, the evidence for patient outcomes such as intubation or mortality is still lacking. Thus we organized this international, multicenter, randomized controlled meta-trial, with 41 hospitals in 6 countries participated. (more…)
Author Interviews, Opiods, Pancreatic, PLoS / 08.01.2021

MedicalResearch.com Interview with: Faraz Bishehsari, MD, PhD Associate Professor of Medicine and Graduate College Director of the Translational Gastroenterology Unit Division of Digestive Diseases Rush University Medical Center MedicalResearch.com: What is the background for this study? Response: This study builds on recent population based studies where opium use was found to be possible risk factor for pancreatic cancer. Although opium use is not a common recreational habit in the United States, opioid use has been rising remarkably over the past decade. In fact, opioid misuse and overdose have evolved into a public health crisis here with increasing opioid prescription use and abuse over the past decade. (more…)
Author Interviews, Cognitive Issues / 23.01.2019

MedicalResearch.com Interview with: Bryan D. James, PhD Assistant Professor Rush Alzheimer's Disease Center Chicago, IL 60612  MedicalResearch.com: What is the background for this study? Response: It has long been reported by patients, their family members, and physicians that many older adults experience long-term declines in their memory and thinking abilities after hospitalization. Studies have recently begun to confirm these reports by following older patients for years after hospitalization and repeatedly testing their cognitive abilities. A number of questions have yet to be answered, including which types of hospitalizations are most strongly related to cognitive decline. In this study, we sought to answer whether going to the hospital for elective procedures was as risky to the cognitive health of older adults as urgent or emergency (that is, non-elective) hospitalizations. (more…)