Pain Research, Stem Cells / 12.12.2024

back-pain-stem-cells

Why is Stem Cell Therapy for Back Pain a Revolutionary Approach?

Data on chronic back pain expose the shockingly global frequency of this disorder. Global studies estimate that back pain is one of the most frequent musculoskeletal conditions affecting around 540 million people at any one time. In contemporary life, bad posture, inactive behavior, and lack of consistent exercise help to explain the growing back pain frequency. Furthermore, aggravating the problem are elements like heavy lifting, repeated actions, and stress. While many people find relief from conventional therapies including medicine and physical therapy, new developments in medical science offer encouraging answers. Stem treatment for back pain is one such cutting-edge method that uses stem cells' capacity for regeneration to heal damaged tissues and reduce persistent pain. Offering those with crippling back pain a chance to restore mobility, comfort, and an enhanced quality of life, this innovative therapy has huge potential to change their life. Offering hope and healing for those with chronic back pain, stem cell therapy has become a breakthrough substitute in the world of medical science in recent years. Stem treatment for back pain employs stem cells' regenerative capacity to target pain's underlying causes and advance tissue healing. Stem cells are injected into the afflicted location in this novel treatment; they have the amazing capacity to develop into various kinds of cells and rebuild damaged tissues. Stem cell treatment for back pain has the ability to give long-lasting relief and enhance the general quality of life for people suffering with this crippling illness by encouraging the body's natural healing process. As the research on using stem cells for lower back advances constantly, this innovative treatment presents a potentially viable path for people looking for a quick and transforming fix for their back discomfort. (more…)
Dermatology / 17.05.2024

Our skin is subject to a multitude of internal and external influences that can affect its thickness and texture over time. Factors such as aging, environmental aggressors, lifestyle choices, and genetics can contribute to the gradual thinning and deterioration of skin quality. However, the good news is that there are various approaches to address these concerns and promote the restoration of skin thickness and texture. In this article, we'll explore a few crucial factors that, according to research, play pivotal roles in this rejuvenation process.

The Proliferation and Migration of Skin Cells

skin-care-dermatologyAccording to the National Institutes of Health, at the core of skin thickness and texture restoration lies the process of cell proliferation and migration. The epidermis, the outermost layer of the skin, constantly undergoes renewal through a process known as epidermal turnover. Stem cells within the basal layer of the epidermis divide and differentiate into keratinocytes. These gradually migrate upward to the skin's surface, replacing old, damaged cells. According to Beyond CellCare, stem cell therapy differs from traditional treatments, which only target the symptoms of skin aging. By fostering cellular repair and renewal, it targets the fundamental mechanisms of aging. Furthermore, certain skincare ingredients and treatments, such as chemical exfoliants and professional procedures like microdermabrasion and chemical peels, can accelerate cell turnover. You’ll also find the use of exosome injection and similar therapy methods involving exosomes becoming popular in this regard. Exosomes facilitate skin cell proliferation and migration by transferring growth factors and signaling molecules. (Please note that exosomes are currently not approved by the Food and Drug Administration (FDA) to treat or diagnose any disease). (more…)
Author Interviews, Heart Disease, Stem Cells / 13.11.2023

MedicalResearch.com Interview with: Prof. Dr. Wolfram-Hubertus Zimmermann Director, Institute of Pharmacology and Toxicology University Medical Center Göttingen Georg-August University Göttingen, Germany   MedicalResearch.com: What is the background for this study? Response: Involvement in research and development in the field of tissue engineered heart repair since 25+ years. Bench-to-bed translation of our research. MedicalResearch.com: How are the stem cell obtained? Response: We make use of induced pluripotent stem cells as starting material to obtain heart muscle cells for the engineering of Engineered Human Myocardium (EHM) and its use as Biological Ventricular Assist Tissue (BioVAT). (more…)
Author Interviews, Brigham & Women's - Harvard, Endocrinology, Fertility, Lancet, OBGYNE / 25.07.2023

MedicalResearch.com Interview with: Raymond M. Anchan, MD, Ph.D. Director, Stem Cell Biology and Regenerative Medicine Research Laboratory Assistant Professor, Harvard Medical School Obstetrics/Gynecology Center for Infertility and Reproductive Surgery Brigham and Women's Hospital MedicalResearch.com: What is the background for this study? Response: As a reproductive endocrinologist, I have the privilege of caring for patients who unfortunately experience premature ovarian insufficiency- Some of these patients are as young as 17 yo. Additionally, a significant number of patients over the years have been reproductive age women who have breast cancer and ovarian failure from chemotherapy.  These patients have been my inspiration to try to find a treatment for them.  Since my earlier days as a neurobiologist and stem cell scientist, it was a natural course for me to seek cell-based therapies that are patient specific using autologous iPSCs. (more…)
Author Interviews, Nature, Stem Cells / 05.09.2022

MedicalResearch.com Interview with: Gianluca Amadei PhD Post-Doctoral Fellow University of Cambridge, UK MedicalResearch.com: What is the background for this study? What are the main findings? Response: The background of this study is that we tried to build a structure that looks and develops like a real mouse embryo using different kinds of mouse stem cells. The main findings are that the resulting structures develop the entire embryonic body axis and the extraembryonic tissues that are required to support embryonic development. Our structures develop to a stage comparable to 8.5 days of embryonic development of the natural mouse embryos and have a brain and neural tube, a beating heart-like structure, gut and primordial germ cells. (more…)