24 Jun ADA 2024: Bisphenol in Canned Foods and Plastics May Play a Role in Type 2 Diabetes Risk

MedicalResearch.com Interview with:

Dr. Hagobian

Todd Hagobian, Ph.D.
pronouns he/him/his
Department Chair & Professor, Kinesiology and Public Health
Cal Poly, San Luis Obispo, CA

MedicalResearch.com: What is the background for this study?

Response: Previous observational studies have shown that urinary BPA is related to Type 2 diabetes risk. Meaning, higher urinary BPA is related to an increased risk of Type 2 diabetes. However, no published study to date has determined whether several days of BPA administration (participants consume BPA) increases the risk of Type 2 diabetes.

MedicalResearch.com: Where is bisphenol found?  Can exposure to bisphenol be limited in everyday life?

Response:  BPA and other bisphenols are found in canned foods and plastics. BPA is one of the most widely used synthetic chemicals and we consume foods that are packed in this chemical. Most of BPA exposure comes from canned foods, and 93% of the US populations has detectable urine levels of BPA. We can limit BPA by reducing canned foods (or purchased BPA free cans) and plastic use.

MedicalResearch.com: What are the main findings?

Response:  4 days of BPA administration decreased insulin sensitivity, compared to placebo. This is important because it sets the foundation for other clinical studies in this area, and provides the first, much-needed evidence that BPA may increase the risk of Type 2 diabetes. It is also important to note that the effect of BPA on reducing insulin sensitivity was a small to medium effect in our data. Other risk factors – obesity, lack of exercise, poor nutrition, genetics – play a larger role in the progression of Type 2 diabetes. 

MedicalResearch.com: What should readers take away from your report?

Response: The take home message is that bisphenol  may potentially play a role in Type 2 diabetes risk. We should be aware of food packaging (e.g., canned food, plastic containers, etc.) and try to avoid purchasing food in these containers.

Citation:

Oral Bisphenol A Administration Decreased Peripheral Insulin Sensitivity in Healthy Adults

ADAM SEAL, STEVEN K. MALIN, ANDREW SCHAFFNER, MICHAEL R. HUBBARD, SARAH K. KEADLE, HANNAH BRUNNER-GAYDOS, ALIA A. ORTIZ, JANE E. NAKAMURA, CLARA MCMAHON, RACHEL BARNETT, ANITA H. KELLEHER, KELLY A. BENNION, SUZANNE PHELAN, TODD HAGOBIAN, San Luis Obispo, CA, New Brunswick, NJ, Gilbert, AZ, San, CA, Seattle, WA, San Francisco, CA
Presented at ADA Scientific Meeting June 2024 https://clinicalupdate.diabetes.org/

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Last Updated on June 24, 2024 by Marie Benz MD FAAD