MedicalResearch.com Interview with:
Luigi Naldi, MD
Director Centro Studi GISED
Department of Dermatology
Azienda Ospedaliera papa Giovanni XXIII
MedicalResearch.com: What is the background for this study? What are the main findings?
Response: The study was the natural continuation of a previous case-control study focusing on risk factors for moderate to severe acne in adolescents. In that study, we documented the role of a westernized diet to influence acne severity, with a low weekly intake of fruits or vegetables, a low consumption of fresh fish and a high consumption of milk especially skim milk, being risk factors for moderate to severe acne. Not surprisingly, also a family history of acne was associated with acne severity.
After completion of our study in adolescents, we realized that very little was known about acne in adults. Hence, we started a new case-control study focusing on risk factors for adult female acne. Besides the role of a family history, we documented that lifestyle factors could play an important role in adult acne. More specifically, being an office worker, and having a high level of reported psychological stress were associated with acne in adult women. In addition, similarly to acne in adolescents, low weekly intake of fruits or vegetables and a low consumption of fresh fish were documented as risk factors.
MedicalResearch.com: What should readers take away from your report?
Response: Potential triggers or risk factors for acne should not be trivialized. Studies like ours could offer evidence to promote secondary prevention of acne, modulating acne severity by non-pharmacological interventions such as stress reduction techniques
MedicalResearch.com: What recommendations do you have for future research as a result of this study?
Response: Our data need confirmation by other independent studies adopting a similar methodology. Ideally, epidemiological studies should be complemented by more fundamental biological studies. One important factor influencing the inflammatory reaction in acne, is the sebaceous lipid composition which could be correlated with the environmental factors we documented.
MedicalResearch.com: Is there anything else you would like to add?
Response: Acne is just one of the several chronic inflammatory skin diseases for which there is a lack of information about avoidable risk factors. More research should be devoted to this area by making a more intensive use of analytic epidemiology research methods.
MedicalResearch.com: Thank you for your contribution to the MedicalResearch.com community.
Adult female acne and associated risk factors: Results of a multicenter case-control study in Italy
Di Landro, Anna et al.
Journal of the American Academy of Dermatology , Volume 75 , Issue 6 , 1134 – 1141.e1
Published online:August 16, 2016
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