Diabetic Severity May Predict Risk of Dementia

MedicalResearch.com Interview with:
Wei-Che Chiu, MD, PhD
National Taiwan University College of Public Health,
Cathay General Hospital and Fu Jen Catholic University
Taipei, Taiwan

Medical Research: What is the background for this study?

Response: Diabetes mellitus is a common risk factor for dementia and accounts
for 6–8% of all cases of dementia in older populations. Cognitive
impairment is associated with the presence of diabetic complications
and diabetic severity, but the effects of diabetic severity on
dementia are unclear. Our study was to investigate the association
between the severity and progress of diabetes and the risk of

Medical Research: What are the main findings?

Response: The diabetic severity and progression reflected the risk
of dementia, and the early progress in diabetic severity could predict
the risk of dementia in new-onset diabetic patients.

Medical Research: What should clinicians and patients take away from your report?


1. The risk of dementia was increased from the diabetes onset and was
associated with the diabetic complication severity and progression.

2. Progress of the diabetic severity in the early years of diabetes
could predict the risk of dementia.

3. The prevention of diabetic progression is important to reduce the
risk of dementia.

4. The diabetic complication severity was another indicator of the
risk of dementia from the blood sugar.

Medical Research: What recommendations do you have for future research as a result of this study?

Response: Because the etiology of dementia is varied, the mechanisms of
the diabetic severity and progression on the different types of
dementia should be further investigated.


Wei-Che Chiu, MD, PhD et al. Progess of Diabetic Severity and Risk of Dementia. Journal of Clinical Endocrinology & Metabolism, July 2015 DOI: 10.1210/jc.2015-1677

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Wei-Che Chiu, MD, PhD (2015). Diabetic Severity May Predict Risk of Dementia