MedicalResearch.com: What are the main findings of the study?
Dr. Ravi: This study suggests that in persons with moderate-severe osteoarthritis of the hip or knee, total joint replacement is associated with a significant reduction in the risks for serious cardiovascular events.
MedicalResearch.com: Were any of the findings unexpected?
Dr. Ravi: The main finding of this study is provocative and warrants further investigation, hopefully in larger studies.
MedicalResearch.com: What should clinicians and patients take away from your report?
Dr. Ravi: Osteoarthritis is associated with significant medical morbidity, and this morbidity is likely proportional to the severity of their underlying OA. This study indicates that managing their Osteoarthritis also has a benefit on these other morbidities.
MedicalResearch.com: What recommendations do you have for future research as a result of this study?
Dr. Ravi: Any future work should utilize a cohort of persons with confirmed arthritis, and hopefully capture information on the same scale as the current project.
Bheeshma Ravi, MD, Toronto, Canada
Ruth Croxford, MSc, Toronto, Canada
Peter Austin, Toronto, Canada
Lorraine Lipscombe, Toronto, Canada
Arlene Bierman, MD, MS, Toronto, Canada
Paula Harvey, MBBS, PhD, Toronto, Canada
Gillian Hawker, MD, Toronto, Canada