08 Nov Low Dose Aspirin May Be Beneficial in Chronic Kidney Disease Patients
MedicalResearch.com Interview with:
Dr. Csaba P. Kovesdy
Csaba P Kovesdy MD FASN
Fred Hatch Professor of Medicine
Director, Clinical Outcomes and Clinical Trials Program
Division of Nephrology, University of Tennessee Health Science Center
Nephrology Section Chief, Memphis VA Medical Center
Memphis TN, 38163
MedicalResearch.com: What is the background for this study?
Response: Microinflammation may be a mechanism contributing to adverse outcomes in patients with chronic kidney disease (CKD). Low dose aspirin (ASA) is usually used as an antiplatelet agent for cardiovascular indications, but may also have beneficial effects on kidney function by reducing microinflammation.
MedicalResearch.com: What are the main findings?
Response: We found an association between long-term aspirin and lower risk of a composite renal outcome and mortality in a single center cohort of patients with CKD.
MedicalResearch.com: What should readers take away from your report?
Response: Aspirin may have beneficial effects in CKD beyond prevention of cardiovascular events.
MedicalResearch.com: What recommendations do you have for future research as a result of this work?
Response: Our results are hypothesis generating and will need to be replicated in larger and more diverse cohorts and potentially in future clinical trials, before we can recommend aspirin for renoprotection.
Citation:
American Society of Nephrology (ASN) 2021 Kidney Week Poster
Association of Long-Term Aspirin Use with Progression of Kidney Disease
Author(s): Jun Ling Lu1; Fridtjof Thomas1; Keiichi Sumida1; Waleed Hassan1; Csaba P. Kovesdy1
1The University of Tennessee Health Science Center, Memphis, Tennessee, United States
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Last Updated on November 8, 2021 by Marie Benz MD FAAD