Low Carb Diet Results In More Weight Loss, Better Lipid Control Than Low Fat Diet

Low Carb Diet Results In More Weight Loss, Better Lipid Control Than Low Fat Diet

MedicalResearch.com Interview with:
Tian Hu, MD, MS Research Fellow
​Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine
New Orleans, LA 70112

Medical Research: What are the main findings of the study?

Dr. Hu: Participants on the low-carbohydrate diet lost more weight than those on the low-fat diet at 3, 6, and 12 months. At 12 months, those in the low-carbohydrate group lost an average of almost 8 pounds more than those in the low-fat group.

Participants on the low-carbohydrate diet lost more fat mass and did not lose lean mass (muscle) compared to those on the low-fat diet.

Overall, bad cholesterol (low-density lipoprotein cholesterol) that is a predictor of risk for cardiovascular disease decreased on both diets, but good cholesterol (high-density lipoprotein cholesterol) increased more in the low-carbohydrate group.

Physical activity was similar in the groups throughout the study, suggesting that the greater weight loss among participants in the low-carbohydrate group was not because they exercised more.

When we evaluated the black and white participants separately, the results were similar.

Medical Research: Were any of the findings unexpected?

Dr. Hu: Low-fat diets have been recommended for weight loss and cardiovascular risk factor reduction for a long time while low-carbohydrate diets are often not recommended because of the thought that increases in saturated fat would worsen heart disease risk factors. However, in our trial participants on the low-carbohydrate diet lost more weight and lowered their heart disease risk factors more than those on the low fat diet.

Medical Research: What should clinicians and patients take away from your report?

Dr. Hu: A low-carbohydrate diet could be a good option for people who want to lose weight and reduce their heart disease risk factors.

Medical Research: What recommendations do you have for future research as a result of this study?

Dr. Hu: Future studies could follow participants for longer periods of time and also investigate possible mechanisms for the effects of low-carbohydrate diets on weight loss and cardiovascular risk factor reduction.

Citation:

Effects of Low-Carbohydrate and Low-Fat Diets A Randomized Trial

Bazzano LA, Hu T, Reynolds K, Yao L, Bunol C, Liu Y, et al. Effects of Low-Carbohydrate and Low-Fat Diets: A Randomized Trial. Ann Intern Med. 2014;161:309-318. doi:10.7326/M14-0180

 

Last Updated on September 2, 2014 by Marie Benz MD FAAD