MedicalResearch.com

Over 9112 medical research interviews to date!
More than 1837 interviews with researchers from JAMA, 313 Lancet, 310 NEJM,
405 BMJ interviews

    • Triclosan in Personal Care Products Can Induce Antibiotic Resistance

      Triclosan in Personal Care Products Can Induce Antibiotic Resistance

      We found triclosan found in personal care products that we use daily could directly induce multi-drug resistance through mutation. Continue reading →Read More »
    • Accurate Measurements Suggest High Salt Intake Leads To Higher Death Rate

      Accurate Measurements Suggest High Salt Intake Leads To Higher Death Rate

      Studies have shown that there is a strong linear relationship between sodium intake and blood pressure and raised blood pressure is a leading cause of death and disability worldwide. Continue reading →Read More »
    • Immaturity Plays Leading Role in Late Preterm Complications

      Immaturity Plays Leading Role in Late Preterm Complications

      Preterm infants are born before 37 weeks gestation, with late preterm neonates defined as infants born between 34 weeks to 37 weeks gestation. Of all preterm births, over 70% of babies are born in the late preterm period. Late preterm births are common, affecting 12.5% of all births in the United States. Continue reading →Read More »
    • Sibling Closeness in Middle School Predicts Differences in College Graduation

      Sibling Closeness in Middle School Predicts Differences in College Graduation

      Xiaoran Sun Department of Human Development and Family Studies The Pennsylvania State University University Park, PA 16802.   MedicalResearch.com: What is the background for this study? Response: College graduation has significant implications for adult life outcomes including for employment, family formation, and health. Continue reading →Read More »
    • Enabling Angioplasty-Ready “Smart” Stents to Detect In-Stent Restenosis and Occlusion

      Enabling Angioplasty-Ready “Smart” Stents to Detect In-Stent Restenosis and Occlusion

      MedicalResearch.com Interview with: Kenichi Takahata, Ph.D., P.Eng. Associate Professor Department of Electrical & Computer Engineering Faculty of Applied Science University of British Columbia Vancouver, B.C., Canada MedicalResearch.com: What is the background for this technology and study?  Response: Cardiovascular disease (CVD) is … Continue reading →Read More »
    • Watson for Clinical Trial Matching Increases Enrollment in Breast Cancer Trials

      Watson for Clinical Trial Matching Increases Enrollment in Breast Cancer Trials

      Alexandra Urman, MPH Clinical Research Manager Clinical Development IBM Watson Health  MedicalResearch.com: What is the background for this study?  Response: Cancer statistics show only 3-5% of cancer patients participate in clinical trials although up to 20% may be eligible. Dr. Tufia Hadad, a medical Oncologist at the Mayo Clinic in Rochester, Minnesota sought to address this issue and spearheaded a project conducted at the Rochester facility in collaboration with IBM Watson Health. The objective was to determine if the use of cognitive computing increased clinical trial enrollment and screening efficiency in the breast cancer clinic. Watson for Clinical Trial Matching (CTM) is a cognitive system which utilizes natural language processing to derive patient and tumor attributes from unstructured text in the electronic health record that can be further used to match a patient to complex eligibility criteria in trial protocols. Continue reading →Read More »
    • Higher Vitamin D Levels Linked to Lower Breast Cancer Incidence

      Higher Vitamin D Levels Linked to Lower Breast Cancer Incidence

      Cedric F. Garland, Dr.P.H., F.A.C.E. Adjunct Professor Division of Epidemiology Department of Family Medicine and Public Health University of California San Diego La Jolla, California 92093-0620 MedicalResearch.com: What is the background for this study? Response: Studies mapping death rates from female breast cancer in the US, the former USSR and Canada by Drs. Edward Gorham, and Frank and Cedric Garland revealed for the first time in history that death rates from breast cancer tracked latitude where people lived. The rates were highest in the least sunny northern tier of states, lowest in the sunny southwest. This led these scientists to be the first to theorize that vitamin D prevents breast cancer” said study first author Sharon McDonnell. Continue reading →Read More »
    • Bisexual Men Face Greater Risk of Heart Disease

      Bisexual Men Face Greater Risk of Heart Disease

      Billy A. Caceres, PhD, RN, AGPCNP-BC NYU Rory Meyers College of Nursing New York, NY 10010 MedicalResearch.com: What is the background for this study? What are the main findings? Response: Although current evidence, primarily based on self-reported data, suggests gay and bisexual men report higher rates of cardiovascular risk factors (such as poor mental health and tobacco use) than heterosexual men, few studies have examined heart disease risk in this population. This study is one of the few studies to examine heart disease risk in gay and bisexual men using biological measures. Continue reading →Read More »
    • Unrelated Bacterial Strains Can Transfer Antibiotic Resistance Genes To Each Other

      Unrelated Bacterial Strains Can Transfer Antibiotic Resistance Genes To Each Other

      MedicalResearch.com Interview with: Richard Stanton, PhD Health Scientist, Division of Healthcare Quality Promotion Centers for Disease Control and Prevention MedicalResearch.com: What is the background for this study? Response: We used whole genome sequencing (WGS) to investigate an outbreak of carbapenem-resistant Enterobacteriaceae (CRE) that occurred in an acute care hospital in Kentucky over a six month period in late 2016. The outbreak included 18 cases of CRE. Continue reading →Read More »
    • No Evidence Probiotics Will Reduce Your Anxiety

      No Evidence Probiotics Will Reduce Your Anxiety

      Daniel Reis MA Graduate Student Clinical Psychology University of Kansas MedicalResearch.com: What is the background for this study? What are the main findings? Probiotics have generated considerable interest as a possible treatment for numerous forms of physical and mental illness. Preliminary evidence from both preclinical and clinical studies suggest that probiotics may be able to reduce anxiety. Our goal was to comprehensively review and summarize existing preclinical and clinical studies. Overall, probiotic administration reduced anxiety-like behaviors in rodents, but only in those with some form of experimentally-induced disease (such as early-life stress or socieal defeat). Probiotics did not reduce anxiety in humans. Continue reading →Read More »
    • Anti-PD1 Immunotherapy May Work Better in Older Melanoma Patients

      Anti-PD1 Immunotherapy May Work Better in Older Melanoma Patients

      Ashani Weeraratna, Ph.D. The Ira Brind professor and Co-program leader of the Immunology, Microenvironment and Metastasis Program The Wistar Institute Member of Wistar’s Melanoma Research Center Philadelphia  MedicalResearch.com: What is the background for this study? What are the main findings?  Response:  This study shows for the first time that older patients, especially those who have had prior MAPKi therapy fare better than younger patients when treated with anti-PD1. We found that tumors in younger patients and younger mice have higher levels of Tregulatory cells, the cells that regulate other immune cells. This is not true systemically, only within the tumor microenvironment. We were surprised because we expected that, as with targeted therapy, older patients would have a poorer response to immunotherapy, given what we perceive as a poorer immune system in older patients.  Continue reading →Read More »
    • Atopic Dermatitis (Eczema) Patients Have Higher Likelihood of Osteoporosis

      Atopic Dermatitis (Eczema) Patients Have Higher Likelihood of Osteoporosis

      Dr. Jonathan L. Silverberg MD PhD MPH Assistant Professor in Dermatology Medical Social Sciences and Preventive Medicine Northwestern University, Chicago, Illinois MedicalResearch.com: What is the background for this study? Response: Persons with atopic dermatitis have a number of risk factors for osteopenia and osteoporosis, including systemic atopy and inflammation, being less physically active and using a lot of topical and/or systemic corticosteroids. We aimed to determine whether adults with atopic dermatitis in fact have higher rates of physician-diagnosed osteopenia and osteoporosis. Continue reading →Read More »
    • Individuals With Very High Levels of Lipoprotein(a) May Benefit Most From LDL(a)-Lowering Drugs

      Individuals With Very High Levels of Lipoprotein(a) May Benefit Most From LDL(a)-Lowering Drugs

      Dr. Stephen Burgess PhD Programme Leader at the Medical Research Council Biostatistics Unit University of Cambridge MedicalResearch.com: What is the background for this study? What are the main findings? Response: Lipoprotein(a) is a lipoprotein subclass, and an important biomarker for coronary heart disease. As a clinical biomarker, it has a similar story to LDL-cholesterol (“bad” cholesterol), in that it is thought to be a causal risk factor for coronary heart disease, and so is a potential target for drug development. However, while drugs that lower LDL-cholesterol, such as statins, have been successful in reducing coronary heart disease risk, drugs that lower lipoprotein(a) have not as yet been successful. New drugs are currently in development that specifically target lipoprotein(a) and can lower lipoprotein(a) concentrations by 80-90%. We performed this study to investigate whether these drugs are likely to be successful in reducing coronary heart disease risk. Continue reading →Read More »
    • Stress Disorders Linked to Increase Risk of Autoimmune Disease

      Stress Disorders Linked to Increase Risk of Autoimmune Disease

      Huan Song Associated Department of Medical Epidemiology and Biostatistics Karolinska Institutet MedicalResearch.com: What is the background for this study? Response: Earlier findings from our group (e.g. Fang et al., NEJM 2012; Arnberg et al., Lancet Psychiatry 2015; Lu et al., JAMA Oncol 2016; Shen et al., BMJ 2016; Zhu et al., Ann Oncol 2017) have identified pathways through which stressful events contribute to deterioration in human health. With strong animal models and human data supporting a role of stress in immune dysregulation, the hypothesis linking mental distress with autoimmune is indeed plausible. However, the evidence is as yet limited to clinical observations and a few larger observational studies on US veterans, most of them on men only, and some of which have cross-sectional designs and various other methodological shortcomings. Continue reading →Read More »
    • Stress Echocardiography vs Coronary CT To Evaluate Chest Pain in ER

      Stress Echocardiography vs Coronary CT To Evaluate Chest Pain in ER

      Jeffrey M. Levsky, M.D., Ph.D. Associate Professor, Department of Radiology Associate Professor, Department of Medicine (Cardiology) Albert Einstein College of Medicine Montefiore Medical Center MedicalResearch.com: What is the background for this study? What are the main findings? Response: Millions of Americans are evaluated each year for acute chest pain in the Emergency Department.  There are multiple modalities that can be used to triage these patients and there have only been a few studies comparing different imaging methods. We chose to study Stress Echocardiography and Coronary CT Angiography, two exams that have not been compared directly in this population.  We found that Stress Echocardiography was able to discharge a higher proportion of patients in a shorter amount of time as compared to Coronary CTA.  Continue reading →Read More »