24 Jun Pre-Labor C-Section Affects Newborn’s Immune System

Prof. Bisgaard

MedicalResearch.com Interview with:
Professor of Pediatrics Hans Bisgaard, MD, DMSc
Copenhagen Prospective Studies on Asthma in Childhood
Herlev and Gentofte Hospital,
University of Copenhagen, Denmark

Medical Research: What is the background for this study?

Prof. Bisgaard: Programming of the immune response in perinatal life seems to contribute to the increased prevalence of immune-mediated diseases

We hypothesized that initiation of labor could affect the developing newborn immune system.

Medical Research: What are the main findings?

Prof. Bisgaard: Pre-labor cesarean section is associated with a distinct and gestational age-related distribution of circulating immune cells in newborns suggesting that changes in specific immune compartments occur during the approach of labor.

Medical Research: What should clinicians and patients take away from your report?

Prof. Bisgaard: This is research attempting to understand factors influencing early immune maturation.

Medical Research: What recommendations do you have for future research as a result of this study?

Prof. Bisgaar: Replication in a larger cohort.

Citation:

Prelabor cesarean section bypasses natural immune cell maturation

Thysen, Anna Hammerich et al.

Journal of Allergy and Clinical Immunology
Published Online: June 17, 2015
DOI: http://dx.doi.org/10.1016/j.jaci.2015.04.044

Pre-labor cesarean section is associated with a distinct and gestational age-related distribution of circulating immune cells in newborns (2015). Pre-Labor C-Section Affects Newborn’s Immune System MedicalResearch.com[wysija_form id=”3″]

Last Updated on November 18, 2015 by Marie Benz MD FAAD